Contraception for Men: A Breakthrough New Approach

There has not been a new reversible contraceptive for men since the development of the condom, centuries ago. Matzuk et al. describe a new molecular approach using administration of a small molecule to directly and reversibly inhibit spermatogenesis in mice by blocking the function of a testicular b...

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Bibliographic Details
Published inCell Vol. 150; no. 4; pp. 667 - 668
Main Author Bremner, William J.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 17.08.2012
Subjects
adverse effects
contraception
contraceptives
men
mice
progeny
spermatogenesis
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Summary:There has not been a new reversible contraceptive for men since the development of the condom, centuries ago. Matzuk et al. describe a new molecular approach using administration of a small molecule to directly and reversibly inhibit spermatogenesis in mice by blocking the function of a testicular bromodomain without apparent adverse effect on the organism or offspring.
Bibliography:http://dx.doi.org/10.1016/j.cell.2012.07.027
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ISSN:0092-8674
1097-4172
DOI:10.1016/j.cell.2012.07.027