Pure red cell aplasia and hepatitis in a child receiving isoniazid therapy

A 7-year-old boy had pure red cell aplasia and clinically significant hepatitis during isoniazid therapy. The former complication had been reported only in adults, and the latter is rare in children.

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Bibliographic Details
Published inThe Journal of pediatrics Vol. 120; no. 1; pp. 146 - 148
Main Authors Veale, Kevin S., Huff, E. Sterling, Nelson, Brian K., Coffman, Donna S.
Format Journal Article
LanguageEnglish
Published New York, NY Mosby, Inc 1992
Elsevier
Subjects
Biological and medical sciences
Chemical and Drug Induced Liver Injury - blood
Chemical and Drug Induced Liver Injury - etiology
Child
Drug toxicity and drugs side effects treatment
Humans
Isoniazid - adverse effects
Male
Medical sciences
Pharmacology. Drug treatments
Red-Cell Aplasia, Pure - blood
Red-Cell Aplasia, Pure - chemically induced
Toxicity: blood
Human
Case study
Hepatitis
Antibiotic
Concomitant disease
Toxicity
Red blood cell
Digestive diseases
Hepatic disease
Hemopathy
Child
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Summary:A 7-year-old boy had pure red cell aplasia and clinically significant hepatitis during isoniazid therapy. The former complication had been reported only in adults, and the latter is rare in children.
ISSN:0022-3476
1097-6833
DOI:10.1016/S0022-3476(05)80621-3