Can chatter between microbes prevent cholera?

Tackling the global rise in antibiotic resistance requires new therapies against infectious microbes. A recent microbiome study identified commensal gut bacteria that reduce colonisation by the cholera pathogen, Vibrio cholerae . This antagonistic interaction might be mediated by quorum sensing, sug...

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Bibliographic Details
Published inTrends in microbiology (Regular ed.) Vol. 22; no. 12; pp. 660 - 662
Main Authors Thompson, Jessica A, Oliveira, Rita Almeida, Xavier, Karina B
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.12.2014
Subjects
AI-2
Animals
bacterial signalling
cell–cell communication
Cholera - microbiology
Humans
Internal Medicine
Intestines - microbiology
LuxS
Male
microbiota
Microbiota - physiology
quorum sensing
Ruminococcus - physiology
Vibrio cholerae - pathogenicity
Vibrio cholerae - physiology
LuxS
microbiota
cell–cell communication
bacterial signalling
quorum sensing
AI-2
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Summary:Tackling the global rise in antibiotic resistance requires new therapies against infectious microbes. A recent microbiome study identified commensal gut bacteria that reduce colonisation by the cholera pathogen, Vibrio cholerae . This antagonistic interaction might be mediated by quorum sensing, suggesting that these natural microbe–microbe interactions can help prevent infectious disease.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Commentary-1
ISSN:0966-842X
1878-4380
DOI:10.1016/j.tim.2014.10.006