Concomitant primary hyperparathyroidism and systemic lupus erythematosus: coincidence or not? A new case report

• Published in: The Pan African medical journal Vol. 37; no. 228; p. 228
• Main Authors: Alaoui, Habiba Bennesser, Hamaz, Siham, Bachir, Houda, Eloumri, Ahmed Amine, Berrimi, Mohammed, Bouayad, Abdellatif, Serraj, Khalid
• Format: Journal Article
• Language: English
• Published: Uganda African Field Epidemiology Network 2020; The African Field Epidemiology Network; The Pan African Medical Journal
• Subjects: Adult; Antiphospholipid Syndrome - diagnosis; Case Report; Case reports; Disease; Female; Humans; Hypercalcemia; Hypercalcemia - diagnosis; Hypercalcemia - etiology; Hyperparathyroidism, Primary - complications; Hyperparathyroidism, Primary - diagnosis; Laboratories; Lupus; Lupus Erythematosus, Systemic - complications; Lupus Nephritis - diagnosis; Medical imaging; Metabolism; Osteoporosis; Osteoporosis - etiology; Patients; primary hyperparathyroidism; Pulmonary Embolism - diagnosis; Pulmonary Embolism - etiology; Pulmonary embolisms; Steroids; systemic lupus erythematosus; Tumor necrosis factor-TNF; Tumors; Ultrasonic imaging; Morocco; Hypercalcemia; case report; systemic lupus erythematosus; primary hyperparathyroidism
• ISSN: 1937-8688; 1937-8688
• DOI: 10.11604/pamj.2020.37.228.26257

Primary hyperparathyroidism (PHP) is the most common cause of hypercalcemia. Patients with systemic lupus erythematosus (SLE) can develop hypercalcemia but it is exceptionally due to PHP. There are only few cases of concurrent SLE and primary hyperparathyroidism (PHP) described in the literature. We report a case of a 31-year-old patient having SLE with lupus nephritis class III and anti-phospholipid syndrome, complicated by pulmonary embolism associated to primary hyperparathyroidism causing severe hypercalcemia and osteoporosis. Even if there is no evidence for potential pathogenic association between PHP and SLE, the recognition of this association is very important because of therapeutic and prognostic impact. Early detection of PHP leads to avoid severe complications and significant morbidity.