Influence of Dopant Nature on Biological Properties of ZnO Thin-Film Coatings on Ti Alloy Substrate

• Published in: Nanomaterials (Basel, Switzerland) Vol. 10; no. 1; p. 129
• Main Authors: Stoleriu, Stefania, Lungu, Codruta, Ghitulica, Cristina Daniela, Surdu, Adrian, Voicu, Georgeta, Cucuruz, Andreia, Turculet, Claudiu Stefan, Ciocan, Lucian Toma
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 10.01.2020; MDPI
• Subjects: Amniotic fluid; Antibacterial activity; antibacterial test; Antimicrobial agents; Bacteria; Biocompatibility; Biological activity; Biological properties; Carbon dioxide; Cell adhesion; Cobalt; Contact angle; Doping; Drug resistance; Energy; Glycerol; Gram-positive bacteria; in-vitro test; Infectious diseases; Magnesium; Morphology; Nanoparticles; Pathogens; Sol-gel processes; Solvents; Spin coating; Stem cells; Substrates; Thin films; Titanium base alloys; Wetting; Zinc oxide; Zinc oxides; zno thin film; United States > US; spin coating; antibacterial test; ZnO thin film; in-vitro test
• ISSN: 2079-4991; 2079-4991
• DOI: 10.3390/nano10010129

In this paper, ZnO and Co /Mg -doped ZnO thin films on TiAlV alloy substrates were obtained. The films were deposited by spin coating of sol-gel precursor solutions and thermally treated at 600 °C for 2 h, in air and slow cooled. The doping ions concentration was 1.0 mol%. The study's aim was to obtain implantable metallic materials with improved biocompatibility and antibacterial qualities. The characteristics of the thin films were assessed from the point of view of microstructure, morphology, wetting properties, antibacterial activity and biological response in the presence of amniotic fluid stem cells (AFSC). The results proved that all deposited samples were nanostructured, suggesting a very good antibacterial effect and proving to be suitable supports for cellular adhesion and proliferation. All properties also depended on the doping ion nature.