Temperature Effects on Force and Actin⁻Myosin Interaction in Muscle: A Look Back on Some Experimental Findings

• Published in: International journal of molecular sciences Vol. 19; no. 5; p. 1538
• Main Author: Ranatunga, K W
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 22.05.2018; MDPI
• Subjects: Actin; Actins - metabolism; Adenosine; Adenosine diphosphate; Adenosine triphosphatase; Adenosine Triphosphate - metabolism; Animals; Heart diseases; Humans; Isometric Contraction; Muscle contraction; Muscle, Skeletal - metabolism; Muscle, Skeletal - physiology; Muscles; Myosin; Myosins - metabolism; Review; Temperature; Temperature dependence; Temperature effects; crossbridge force; crossbridge cycle; endothermic force; muscle force; muscle shortening; actin–myosin; temperature-sensitivity

Observations made in temperature studies on mammalian muscle during force development, shortening, and lengthening, are re-examined. The isometric force in active muscle goes up substantially on warming from less than 10 °C to temperatures closer to physiological (>30 °C), and the sigmoidal tempe...