Advancements in Assessments of Bio-Tissue Engineering and Viable Cell Delivery Matrices Using Bile Acid-Based Pharmacological Biotechnologies

The utilisation of bioartificial organs is of significant interest to many due to their versatility in treating a wide range of disorders. Microencapsulation has a potentially significant role in such organs. In order to utilise microcapsules, accurate characterisation and analysis is required to as...

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Published inNanomaterials (Basel, Switzerland) Vol. 11; no. 7; p. 1861
Main Authors Mooranian, Armin, Jones, Melissa, Ionescu, Corina Mihaela, Walker, Daniel, Wagle, Susbin Raj, Kovacevic, Bozica, Chester, Jacqueline, Foster, Thomas, Johnston, Edan, Mikov, Momir, Al-Salami, Hani
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 19.07.2021
MDPI
Subjects
Acids
Artificial organs
Bile
bioartificial organ
Biocompatibility
Biotechnology
cell microencapsulation
Fourier transforms
Hydrogels
immunogenic considerations
Immunogenicity
in vitro testing
microcapsule analysis
Microcapsules
Microencapsulation
Morphology
Pancreas
Permeability
Polymers
Review
Scanning electron microscopy
Spectrum analysis
Tissue engineering
Topography
bioartificial organ
immunogenic considerations
microcapsule analysis
cell microencapsulation
in vitro testing
Online AccessGet full text
ISSN2079-4991
2079-4991
DOI10.3390/nano11071861

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Abstract The utilisation of bioartificial organs is of significant interest to many due to their versatility in treating a wide range of disorders. Microencapsulation has a potentially significant role in such organs. In order to utilise microcapsules, accurate characterisation and analysis is required to assess their properties and suitability. Bioartificial organs or transplantable microdevices must also account for immunogenic considerations, which will be discussed in detail. One of the most characterized cases is the investigation into a bioartificial pancreas, including using microencapsulation of islets or other cells, and will be the focus subject of this review. Overall, this review will discuss the traditional and modern technologies which are necessary for the characterisation of properties for transplantable microdevices or organs, summarizing analysis of the microcapsule itself, cells and finally a working organ. Furthermore, immunogenic considerations of such organs are another important aspect which is addressed within this review. The various techniques, methodologies, advantages, and disadvantages will all be discussed. Hence, the purpose of this review is providing an updated examination of all processes for the analysis of a working, biocompatible artificial organ.
AbstractList The utilisation of bioartificial organs is of significant interest to many due to their versatility in treating a wide range of disorders. Microencapsulation has a potentially significant role in such organs. In order to utilise microcapsules, accurate characterisation and analysis is required to assess their properties and suitability. Bioartificial organs or transplantable microdevices must also account for immunogenic considerations, which will be discussed in detail. One of the most characterized cases is the investigation into a bioartificial pancreas, including using microencapsulation of islets or other cells, and will be the focus subject of this review. Overall, this review will discuss the traditional and modern technologies which are necessary for the characterisation of properties for transplantable microdevices or organs, summarizing analysis of the microcapsule itself, cells and finally a working organ. Furthermore, immunogenic considerations of such organs are another important aspect which is addressed within this review. The various techniques, methodologies, advantages, and disadvantages will all be discussed. Hence, the purpose of this review is providing an updated examination of all processes for the analysis of a working, biocompatible artificial organ.
The utilisation of bioartificial organs is of significant interest to many due to their versatility in treating a wide range of disorders. Microencapsulation has a potentially significant role in such organs. In order to utilise microcapsules, accurate characterisation and analysis is required to assess their properties and suitability. Bioartificial organs or transplantable microdevices must also account for immunogenic considerations, which will be discussed in detail. One of the most characterized cases is the investigation into a bioartificial pancreas, including using microencapsulation of islets or other cells, and will be the focus subject of this review. Overall, this review will discuss the traditional and modern technologies which are necessary for the characterisation of properties for transplantable microdevices or organs, summarizing analysis of the microcapsule itself, cells and finally a working organ. Furthermore, immunogenic considerations of such organs are another important aspect which is addressed within this review. The various techniques, methodologies, advantages, and disadvantages will all be discussed. Hence, the purpose of this review is providing an updated examination of all processes for the analysis of a working, biocompatible artificial organ.The utilisation of bioartificial organs is of significant interest to many due to their versatility in treating a wide range of disorders. Microencapsulation has a potentially significant role in such organs. In order to utilise microcapsules, accurate characterisation and analysis is required to assess their properties and suitability. Bioartificial organs or transplantable microdevices must also account for immunogenic considerations, which will be discussed in detail. One of the most characterized cases is the investigation into a bioartificial pancreas, including using microencapsulation of islets or other cells, and will be the focus subject of this review. Overall, this review will discuss the traditional and modern technologies which are necessary for the characterisation of properties for transplantable microdevices or organs, summarizing analysis of the microcapsule itself, cells and finally a working organ. Furthermore, immunogenic considerations of such organs are another important aspect which is addressed within this review. The various techniques, methodologies, advantages, and disadvantages will all be discussed. Hence, the purpose of this review is providing an updated examination of all processes for the analysis of a working, biocompatible artificial organ.
Author Ionescu, Corina Mihaela
Walker, Daniel
Wagle, Susbin Raj
Mooranian, Armin
Foster, Thomas
Mikov, Momir
Chester, Jacqueline
Al-Salami, Hani
Johnston, Edan
Jones, Melissa
Kovacevic, Bozica
AuthorAffiliation 3 Department of Pharmacology, Toxicology and Clinical Pharmacology, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21101 Novi Sad, Serbia; momir.mikov@mf.uns.ac.rs
2 Hearing Therapeutics, Ear Science Institute Australia, Queen Elizabeth II Medical Centre, Nedlands, Perth, WA 6009, Australia
1 The Biotechnology and Drug Development Research Laboratory, Curtin Medical School, Curtin Health Innovation Research Institute, Curtin University, Bentley, Perth, WA 6102, Australia; a.mooranian@curtin.edu.au (A.M.); melissa.a.jones@student.curtin.edu.au (M.J.); c.ionescu@postgrad.curtin.edu.au (C.M.I.); danieljcswalker@gmail.com (D.W.); susbinraj.wagle@postgrad.curtin.edu.au (S.R.W.); bozica.kovacevic@postgrad.curtin.edu.au (B.K.); j.chester@graduate.curtin.edu.au (J.C.); thomas.p.foster@student.curtin.edu.au (T.F.); edan.johnston@student.curtin.edu.au (E.J.)
AuthorAffiliation_xml – name: 1 The Biotechnology and Drug Development Research Laboratory, Curtin Medical School, Curtin Health Innovation Research Institute, Curtin University, Bentley, Perth, WA 6102, Australia; a.mooranian@curtin.edu.au (A.M.); melissa.a.jones@student.curtin.edu.au (M.J.); c.ionescu@postgrad.curtin.edu.au (C.M.I.); danieljcswalker@gmail.com (D.W.); susbinraj.wagle@postgrad.curtin.edu.au (S.R.W.); bozica.kovacevic@postgrad.curtin.edu.au (B.K.); j.chester@graduate.curtin.edu.au (J.C.); thomas.p.foster@student.curtin.edu.au (T.F.); edan.johnston@student.curtin.edu.au (E.J.)
– name: 3 Department of Pharmacology, Toxicology and Clinical Pharmacology, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21101 Novi Sad, Serbia; momir.mikov@mf.uns.ac.rs
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Cites_doi 10.1016/j.femsle.2005.08.051
10.3390/scipharm87030020
10.7171/jbt.15-2602-003
10.1177/0963689718809918
10.1016/j.biomaterials.2012.04.039
10.1016/j.ijpharm.2007.03.047
10.3109/03639045.2013.763817
10.1080/03601230802599019
10.1007/978-1-4939-6364-5_24
10.1016/j.addr.2010.01.005
10.3109/03009734.2014.965290
10.1007/s40472-020-00300-3
10.1038/s41598-020-59448-8
10.1172/JCI58447
10.1007/s12247-014-9182-5
10.1002/jbm.a.31630
10.1007/s12562-015-0959-3
10.3109/10717544.2015.1110846
10.3109/10837450.2010.502898
10.1021/ac900881z
10.1002/stem.1096
10.1208/s12249-008-9041-0
10.2174/156720112802650716
10.1007/s13346-015-0268-5
10.1111/j.1574-6941.2002.tb00907.x
10.1159/000345873
10.1172/JCI200215318
10.1038/nmat3525
10.3390/mi12030304
10.1021/acsami.5b08907
10.1016/j.jneumeth.2008.10.009
10.1007/s10616-015-9909-2
10.1073/pnas.0712168105
10.1046/j.1525-1594.2002.06853.x
10.1038/s41598-020-64355-z
10.1080/21691401.2017.1362416
10.1900/RDS.2017.14.51
10.1016/j.carbpol.2008.08.019
10.1016/S0378-5173(03)00201-1
10.1016/j.bbrc.2010.06.022
10.1088/1742-6596/522/1/012025
10.1186/1746-4811-4-15
10.1007/s40204-016-0049-3
10.1002/jbm.a.31033
10.1186/s13071-016-1528-z
10.3389/fmicb.2019.02582
10.3109/21691401.2014.934457
10.1007/s00125-001-0729-x
10.1007/s12195-016-0441-z
10.1016/j.humimm.2016.08.012
10.1002/btpr.2223
10.1038/s41421-020-0159-x
10.3389/fimmu.2018.02514
10.3109/21691401.2015.1058807
10.1016/j.addr.2013.09.015
10.1002/jcp.10357
10.1093/rb/rbw001
10.1155/2011/459251
10.1900/RDS.2010.7.62
10.1016/j.jconrel.2008.08.010
10.3727/215517915X689047
10.1371/journal.pone.0091268
10.1007/s11095-016-1863-y
10.1016/j.actbio.2010.12.006
10.3727/096368910X515872
10.1002/bp060185z
10.1016/j.addr.2013.07.010
10.1016/j.actbio.2013.08.002
10.2337/diabetes.51.1.55
10.1007/978-1-4614-4118-2
10.1007/s11538-010-9524-5
10.1371/journal.pone.0033023
10.1208/s12249-014-0205-9
10.1097/01.tp.0000264555.46417.7d
10.1038/s41598-019-47153-0
10.1002/0471142735.ima03bs111
10.1371/journal.pone.0073498
10.1039/C8BM00518D
10.4103/0975-7406.76463
10.1002/app.28997
10.1002/sctm.19-0019
10.1016/j.tem.2009.12.010
10.1186/s12575-017-0056-3
10.1016/j.addr.2007.08.034
10.1210/er.2018-00154
10.3727/096368915X688461
10.1016/j.biomaterials.2005.05.007
10.3109/21691401.2015.1024845
10.1002/sca.21041
10.1071/CH06197
10.1016/j.biomaterials.2009.09.045
10.1152/ajpcell.00247.2006
10.1002/bit.10577
10.1080/17425247.2016.1178233
10.1016/j.ijbiomac.2017.10.170
10.1007/s12010-010-8975-3
10.3389/fphar.2020.00679
10.3748/wjg.15.804
10.2337/db12-1553
10.1080/15321810903084863
10.1039/C9RA05196A
10.1189/jlb.1104649
10.1042/BJ20110162
10.3109/02652048.2014.958204
10.1186/s40494-019-0304-8
10.1371/journal.pone.0234125
10.1007/s12195-017-0510-y
10.3109/21691401.2014.971806
10.1002/btpr.1734
10.1371/journal.pone.0040868
10.1038/s41598-020-60947-x
10.1002/jbm.a.31472
10.1038/s41598-017-10359-1
10.1111/j.1365-2567.2012.03554.x
10.1021/acsomega.9b03145
10.1371/journal.pone.0231634
10.3389/fbioe.2020.00665
10.1007/s00125-013-2921-1
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Keywords bioartificial organ
immunogenic considerations
microcapsule analysis
cell microencapsulation
in vitro testing
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References Monte (ref_19) 2009; 15
Daoud (ref_76) 2010; 19
Vaithilingam (ref_106) 2017; 7
Khan (ref_26) 2020; 10
Piccinini (ref_94) 2017; 19
Weir (ref_130) 2013; 56
Salic (ref_103) 2008; 105
Mooranian (ref_59) 2014; 44
Chang (ref_112) 2008; 87
Neves (ref_125) 2020; 8
Elizondo (ref_36) 2020; 10
Chan (ref_99) 2013; 12
ref_132
ref_96
Viana (ref_114) 2016; 9
Wu (ref_131) 2007; 292
Smink (ref_68) 2013; 62
Wang (ref_2) 2019; 28
Werner (ref_91) 2013; 29
Wilson (ref_117) 2008; 60
ref_18
ref_16
Li (ref_82) 2006; 22
Hamel (ref_66) 2002; 45
Lindblom (ref_107) 2015; 120
Padet (ref_101) 2009; 30
Negrulj (ref_27) 2015; 44
Maedler (ref_120) 2002; 110
Strober (ref_93) 2015; 111
Teramura (ref_62) 2010; 62
Maier (ref_128) 2006; 12
Newbury (ref_30) 2013; 35
Spasojevic (ref_57) 2012; 33
Singh (ref_47) 2009; 44
Pareta (ref_67) 2013; 80
Mooranian (ref_24) 2014; 8
Fooks (ref_105) 2002; 39
(ref_21) 2007; 341
Sauerzweig (ref_100) 2009; 177
Mooranian (ref_85) 2016; 6
Spasojevic (ref_46) 2014; 2
Krishnan (ref_6) 2017; 1479
Rokstad (ref_25) 2014; 67–68
Mathavan (ref_52) 2016; 23
Foster (ref_75) 2007; 83
Orive (ref_8) 2003; 259
Kamps (ref_55) 2007; 80
Prajapati (ref_23) 2008; 9
ref_70
Barshes (ref_116) 2005; 77
Leuvenink (ref_74) 2003; 67
Koss (ref_126) 2011; 2011
Banks (ref_97) 2011; 73
Kouisni (ref_12) 2009; 111
ref_79
Jonkman (ref_14) 2015; 26
Vaithilingam (ref_118) 2017; 14
Awasthi (ref_43) 2012; 9
Steele (ref_73) 2014; 67
Mooranian (ref_45) 2015; 32
Hathout (ref_13) 2018; 108
Tang (ref_15) 2015; 7
Gerencser (ref_129) 2009; 81
Mooranian (ref_58) 2014; 16
Mooranian (ref_56) 2017; 46
Lin (ref_78) 2020; 6
Gill (ref_41) 2010; 21
Mooranian (ref_48) 2014; 9
ref_83
Mooranian (ref_5) 2014; 44
Mooranian (ref_4) 2016; 9
Nasaruddin (ref_49) 2020; 16
Thanos (ref_10) 2007; 83
Aijaz (ref_63) 2019; 8
Lee (ref_119) 2010; 397
Kelly (ref_65) 2005; 252
Ajun (ref_22) 2009; 75
ref_88
ref_87
Pang (ref_102) 2003; 197
Faustino (ref_20) 2016; 13
Wagle (ref_9) 2020; 10
Sasaki (ref_84) 2019; 9
Donath (ref_113) 2010; 21
Scharp (ref_72) 2013; 67–68
Azadi (ref_35) 2016; 5
Slater (ref_29) 2014; 522
Thanos (ref_64) 2007; 81
Busscher (ref_34) 2003; 67
Tam (ref_38) 2011; 7
ref_53
Rickels (ref_61) 2019; 40
Jahnke (ref_3) 2002; 26
Ichikawa (ref_127) 2012; 136
Piemonti (ref_121) 2002; 51
Mooranian (ref_92) 2016; 32
Koyanagi (ref_89) 2016; 68
Ravassard (ref_81) 2011; 121
Chiu (ref_44) 2011; 3
Rataj (ref_98) 2016; 77
Jiin (ref_51) 2000; 1
Manay (ref_1) 2020; 7
Su (ref_123) 2010; 31
Negrulj (ref_122) 2013; 1
Noguchi (ref_77) 2015; 8
Pareta (ref_69) 2012; 1
Zhao (ref_54) 2019; 9
Anderson (ref_110) 2016; 3
Nishizawa (ref_124) 2016; 82
Strand (ref_11) 2003; 82
Lindblom (ref_109) 2016; 25
Truernit (ref_17) 2008; 4
Vogt (ref_32) 2019; 10
Mooranian (ref_86) 2016; 33
Vaithilingam (ref_80) 2010; 7
Mooranian (ref_95) 2018; 11
(ref_60) 2006; 59
ref_39
Margariti (ref_31) 2019; 7
Takka (ref_42) 2010; 17
Chan (ref_50) 2013; 9
Brand (ref_133) 2011; 435
ref_108
Murua (ref_71) 2008; 132
Kedziorek (ref_104) 2012; 30
Bernard (ref_111) 2018; 6
Chiappe (ref_40) 2019; 4
Xiao (ref_90) 2010; 162
Luukkainen (ref_115) 2018; 9
Awasthi (ref_28) 2014; 40
Mathavan (ref_33) 2016; 44
ref_7
Tam (ref_37) 2005; 26
References_xml – volume: 252
  start-page: 153
  year: 2005
  ident: ref_65
  article-title: Correlation of probiotic Lactobacillus salivarius growth phase with its cell wall-associated proteome
  publication-title: FEMS Microbiol. Lett.
  doi: 10.1016/j.femsle.2005.08.051
– ident: ref_53
  doi: 10.3390/scipharm87030020
– volume: 26
  start-page: 54
  year: 2015
  ident: ref_14
  article-title: Any Way You Slice It-A Comparison of Confocal Microscopy Techniques
  publication-title: J. Biomol. Tech.
  doi: 10.7171/jbt.15-2602-003
– volume: 16
  start-page: 280
  year: 2020
  ident: ref_49
  article-title: Alginate and alginate composites for biomedical applications
  publication-title: Asian J. Pharm. Sci.
– volume: 28
  start-page: 5
  year: 2019
  ident: ref_2
  article-title: Bioartificial Organ Manufacturing Technologies
  publication-title: Cell Transplant.
  doi: 10.1177/0963689718809918
– volume: 33
  start-page: 5552
  year: 2012
  ident: ref_57
  article-title: The association between in vivo physicochemical changes and inflammatory responses against alginate based microcapsules
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2012.04.039
– volume: 341
  start-page: 230
  year: 2007
  ident: ref_21
  article-title: Controlling of systemic absorption of gliclazide through incorporation into alginate beads
  publication-title: Int. J. Pharm.
  doi: 10.1016/j.ijpharm.2007.03.047
– volume: 40
  start-page: 398
  year: 2014
  ident: ref_28
  article-title: Development of novel gastroretentive drug delivery system of gliclazide: Hollow beads
  publication-title: Drug Dev. Ind. Pharm.
  doi: 10.3109/03639045.2013.763817
– volume: 44
  start-page: 113
  year: 2009
  ident: ref_47
  article-title: The controlled and sustained release of a fungicide from starch and alginate beads
  publication-title: J. Environ. Sci. Health Part B
  doi: 10.1080/03601230802599019
– volume: 1479
  start-page: 305
  year: 2017
  ident: ref_6
  article-title: Immunological Challenges Facing Translation of Alginate Encapsulated Porcine Islet Xenotransplantation to Human Clinical Trials
  publication-title: Methods Mol. Biol.
  doi: 10.1007/978-1-4939-6364-5_24
– volume: 62
  start-page: 827
  year: 2010
  ident: ref_62
  article-title: Bioartificial pancreas microencapsulation and conformal coating of islet of Langerhans
  publication-title: Adv. Drug Deliv. Rev.
  doi: 10.1016/j.addr.2010.01.005
– volume: 120
  start-page: 28
  year: 2015
  ident: ref_107
  article-title: A novel model for studies of blood-mediated long-term responses to cellular transplants
  publication-title: Upsala J. Med Sci.
  doi: 10.3109/03009734.2014.965290
– volume: 7
  start-page: 223
  year: 2020
  ident: ref_1
  article-title: Role of Whole Organ Pancreas Transplantation in the Day of Bioartificial and Artificial Pancreas
  publication-title: Curr. Transplant. Rep.
  doi: 10.1007/s40472-020-00300-3
– volume: 10
  start-page: 2368
  year: 2020
  ident: ref_26
  article-title: Power of Scanning Electron Microscopy and Energy Dispersive X-Ray Analysis in Rapid Microbial Detection and Identification at the Single Cell Level
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-020-59448-8
– volume: 121
  start-page: 3589
  year: 2011
  ident: ref_81
  article-title: A genetically engineered human pancreatic β cell line exhibiting glucose-inducible insulin secretion
  publication-title: J. Clin. Investig.
  doi: 10.1172/JCI58447
– volume: 1
  start-page: 49
  year: 2013
  ident: ref_122
  article-title: Potentials and Limitations of Bile Acids in Type 2 Diabetes Mellitus: Applications of Microencapsulation as a Novel Oral Delivery System
  publication-title: J. Endocrinol. Diabetes Mellit.
– volume: 9
  start-page: 150
  year: 2014
  ident: ref_48
  article-title: Stability and Release Kinetics of an Advanced Gliclazide-Cholic Acid Formulation: The Use of Artificial-Cell Microencapsulation in Slow Release Targeted Oral Delivery of Antidiabetics
  publication-title: J. Pharm. Innov.
  doi: 10.1007/s12247-014-9182-5
– volume: 87
  start-page: 676
  year: 2008
  ident: ref_112
  article-title: Lymphocyte/macrophage interactions: Biomaterial surface-dependent cytokine, chemokine, and matrix protein production
  publication-title: J. Biomed. Mater. Res. A
  doi: 10.1002/jbm.a.31630
– volume: 1
  start-page: 252
  year: 2012
  ident: ref_69
  article-title: Bioartificial pancreas: Evaluation of crucial barriers to clinical application
  publication-title: Organ Donation Transplant. Public Policy Clin. Perspect.
– volume: 82
  start-page: 357
  year: 2016
  ident: ref_124
  article-title: Conjugation with alginate oligosaccharide via the controlled Maillard reaction in a dry state is an effective method for the preparation of salmon myofibrillar protein with excellent anti-inflammatory activity
  publication-title: Fish. Sci.
  doi: 10.1007/s12562-015-0959-3
– volume: 23
  start-page: 2869
  year: 2016
  ident: ref_52
  article-title: A comprehensive study of novel microcapsules incorporating gliclazide and a permeation enhancing bile acid: Hypoglycemic effect in an animal model of Type-1 diabetes
  publication-title: Drug Deliv.
  doi: 10.3109/10717544.2015.1110846
– volume: 17
  start-page: 23
  year: 2010
  ident: ref_42
  article-title: Bile salt-reinforced alginate-chitosan beads
  publication-title: Pharm. Dev. Technol.
  doi: 10.3109/10837450.2010.502898
– volume: 81
  start-page: 6868
  year: 2009
  ident: ref_129
  article-title: Quantitative microplate-based respirometry with correction for oxygen diffusion
  publication-title: Anal. Chem.
  doi: 10.1021/ac900881z
– ident: ref_83
– volume: 30
  start-page: 1286
  year: 2012
  ident: ref_104
  article-title: X-ray-visible microcapsules containing mesenchymal stem cells improve hind limb perfusion in a rabbit model of peripheral arterial disease
  publication-title: Stem Cells
  doi: 10.1002/stem.1096
– volume: 9
  start-page: 224
  year: 2008
  ident: ref_23
  article-title: Design and development of gliclazide mucoadhesive microcapsules: In vitro and in vivo evaluation
  publication-title: AAPS PharmSciTech
  doi: 10.1208/s12249-008-9041-0
– volume: 9
  start-page: 437
  year: 2012
  ident: ref_43
  article-title: Development of novel gastroretentive floating particulate drug delivery system of gliclazide
  publication-title: Curr. Drug Deliv.
  doi: 10.2174/156720112802650716
– volume: 6
  start-page: 17
  year: 2016
  ident: ref_85
  article-title: The incorporation of water-soluble gel matrix into bile acid-based microcapsules for the delivery of viable β-cells of the pancreas, in diabetes treatment: Biocompatibility and functionality studies
  publication-title: Drug Deliv. Transl. Res.
  doi: 10.1007/s13346-015-0268-5
– volume: 39
  start-page: 67
  year: 2002
  ident: ref_105
  article-title: In vitro investigations of the effect of probiotics and prebiotics on selected human intestinal pathogens
  publication-title: FEMS Microbiol. Ecol.
  doi: 10.1111/j.1574-6941.2002.tb00907.x
– volume: 80
  start-page: 194
  year: 2013
  ident: ref_67
  article-title: Design of a bioartificial pancreas
  publication-title: Pathobiol. J. Immunopathol. Mol. Cell. Biol.
  doi: 10.1159/000345873
– volume: 110
  start-page: 851
  year: 2002
  ident: ref_120
  article-title: Glucose-induced β cell production of IL-1β contributes to glucotoxicity in human pancreatic islets
  publication-title: J. Clin. Investig.
  doi: 10.1172/JCI200215318
– volume: 12
  start-page: 268
  year: 2013
  ident: ref_99
  article-title: MRI-detectable pH nanosensors incorporated into hydrogels for in vivo sensing of transplanted-cell viability
  publication-title: Nat. Mater.
  doi: 10.1038/nmat3525
– ident: ref_18
  doi: 10.3390/mi12030304
– volume: 7
  start-page: 25077
  year: 2015
  ident: ref_15
  article-title: Facile Synthesis of Biocompatible Fluorescent Nanoparticles for Cellular Imaging and Targeted Detection of Cancer Cells
  publication-title: ACS Appl. Mater. Interfaces
  doi: 10.1021/acsami.5b08907
– volume: 177
  start-page: 149
  year: 2009
  ident: ref_100
  article-title: Time-dependent segmentation of BrdU-signal leads to late detection problems in studies using BrdU as cell label or proliferation marker
  publication-title: J. Neurosci. Methods
  doi: 10.1016/j.jneumeth.2008.10.009
– volume: 68
  start-page: 1489
  year: 2016
  ident: ref_89
  article-title: A comparative study of colorimetric cell proliferation assays in immune cells
  publication-title: Cytotechnology
  doi: 10.1007/s10616-015-9909-2
– volume: 105
  start-page: 2415
  year: 2008
  ident: ref_103
  article-title: A chemical method for fast and sensitive detection of DNA synthesis in vivo
  publication-title: Proc. Natl. Acad. Sci. USA
  doi: 10.1073/pnas.0712168105
– volume: 26
  start-page: 111
  year: 2002
  ident: ref_3
  article-title: MTS Colorimetric Assay in Combination with a Live-Dead Assay for Testing Encapsulated L929 Fibroblasts in Alginate Poly-l-Lysine Microcapsules In vitro
  publication-title: Artif. Organs
  doi: 10.1046/j.1525-1594.2002.06853.x
– volume: 10
  start-page: 7715
  year: 2020
  ident: ref_9
  article-title: Micro-Nano formulation of bile-gut delivery: Rheological, stability and cell survival, basal and maximum respiration studies
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-020-64355-z
– volume: 46
  start-page: 1156
  year: 2017
  ident: ref_56
  article-title: Electrokinetic potential-stabilization by bile acid-microencapsulating formulation of pancreatic β-cells cultured in high ratio poly-L-ornithine-gel hydrogel colloidal dispersion: Applications in cell-biomaterials, tissue engineering and biotechnological applications
  publication-title: Artif Cells Nanomed Biotechnol
  doi: 10.1080/21691401.2017.1362416
– volume: 14
  start-page: 51
  year: 2017
  ident: ref_118
  article-title: Encapsulated Islet Transplantation: Where Do We Stand?
  publication-title: Rev. Diabet. Stud.
  doi: 10.1900/RDS.2017.14.51
– volume: 75
  start-page: 566
  year: 2009
  ident: ref_22
  article-title: Preparation of aspirin and probucol in combination loaded chitosan nanoparticles and in vitro release study
  publication-title: Carbohydr. Polym.
  doi: 10.1016/j.carbpol.2008.08.019
– volume: 259
  start-page: 57
  year: 2003
  ident: ref_8
  article-title: Development and optimisation of alginate-PMCG-alginate microcapsules for cell immobilisation
  publication-title: Int. J. Pharm.
  doi: 10.1016/S0378-5173(03)00201-1
– volume: 397
  start-page: 735
  year: 2010
  ident: ref_119
  article-title: Tauroursodeoxycholate (TUDCA), chemical chaperone, enhances function of islets by reducing ER stress
  publication-title: Biochem. Biophys. Res. Commun.
  doi: 10.1016/j.bbrc.2010.06.022
– volume: 522
  start-page: 012025
  year: 2014
  ident: ref_29
  article-title: Understanding the limitations of the Super-X energy dispersive x-ray spectrometer as a function of specimen tilt angle for tomographic data acquisition in the S/TEM
  publication-title: J. Phys. Conf. Ser.
  doi: 10.1088/1742-6596/522/1/012025
– volume: 4
  start-page: 15
  year: 2008
  ident: ref_17
  article-title: A simple way to identify non-viable cells within living plant tissue using confocal microscopy
  publication-title: Plant Methods
  doi: 10.1186/1746-4811-4-15
– volume: 5
  start-page: 101
  year: 2016
  ident: ref_35
  article-title: Co-encapsulation of pancreatic islets and pentoxifylline in alginate-based microcapsules with enhanced immunosuppressive effects
  publication-title: Prog. Biomater.
  doi: 10.1007/s40204-016-0049-3
– volume: 81
  start-page: 1
  year: 2007
  ident: ref_64
  article-title: Stability of alginate-polyornithine microcapsules is profoundly dependent on the site of transplantation
  publication-title: J. Biomed. Mater. Res. A
  doi: 10.1002/jbm.a.31033
– volume: 9
  start-page: 250
  year: 2016
  ident: ref_114
  article-title: Application of rapid in vitro co-culture system of macrophages and T-cell subsets to assess the immunogenicity of dogs vaccinated with live attenuated Leishmania donovani centrin deleted parasites (LdCen−/−)
  publication-title: Parasit. Vectors
  doi: 10.1186/s13071-016-1528-z
– volume: 10
  start-page: 2582
  year: 2019
  ident: ref_32
  article-title: Fourier-Transform Infrared (FTIR) Spectroscopy for Typing of Clinical Enterobacter cloacae Complex Isolates
  publication-title: Front. Microbiol.
  doi: 10.3389/fmicb.2019.02582
– volume: 44
  start-page: 194
  year: 2014
  ident: ref_59
  article-title: Characterization of a novel bile acid-based delivery platform for microencapsulated pancreatic β-cells
  publication-title: Artif. Cells Nanomed. Biotechnol.
  doi: 10.3109/21691401.2014.934457
– volume: 45
  start-page: 159
  year: 2002
  ident: ref_66
  article-title: Considerations for successful transplantation of encapsulated pancreatic islets
  publication-title: Diabetologia
  doi: 10.1007/s00125-001-0729-x
– volume: 9
  start-page: 530
  year: 2016
  ident: ref_4
  article-title: Biological Assessments of Encapsulated Pancreatic β-Cells: Their Potential Transplantation in Diabetes
  publication-title: Cell. Mol. Bioeng.
  doi: 10.1007/s12195-016-0441-z
– volume: 77
  start-page: 1215
  year: 2016
  ident: ref_98
  article-title: Assessment of lymphocyte proliferation for diagnostic purpose: Comparison of CFSE staining, Ki-67 expression and 3H-thymidine incorporation
  publication-title: Hum. Immunol.
  doi: 10.1016/j.humimm.2016.08.012
– volume: 32
  start-page: 501
  year: 2016
  ident: ref_92
  article-title: Designing anti-diabetic β-cells microcapsules using polystyrenic sulfonate, polyallylamine, and a tertiary bile acid: Morphology, bioenergetics, and cytokine analysis
  publication-title: Biotechnol. Prog.
  doi: 10.1002/btpr.2223
– volume: 6
  start-page: 20
  year: 2020
  ident: ref_78
  article-title: In vitro expansion of pancreatic islet clusters facilitated by hormones and chemicals
  publication-title: Cell Discov.
  doi: 10.1038/s41421-020-0159-x
– volume: 9
  start-page: 2514
  year: 2018
  ident: ref_115
  article-title: A Co-culture Model of PBMC and Stem Cell Derived Human Nasal Epithelium Reveals Rapid Activation of NK and Innate T Cells Upon Influenza A Virus Infection of the Nasal Epithelium
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2018.02514
– volume: 1
  start-page: 59
  year: 2000
  ident: ref_51
  article-title: Development of new polycations for cell encapsulation with alginate
  publication-title: Mater. Sci. Eng.
– volume: 44
  start-page: 1508
  year: 2016
  ident: ref_33
  article-title: The role of the bile acid chenodeoxycholic acid in the targeted oral delivery of the anti-diabetic drug gliclazide, and its applications in type 1 diabetes
  publication-title: Artif. Cells Nanomed. Biotechnol.
  doi: 10.3109/21691401.2015.1058807
– volume: 67
  start-page: 74
  year: 2014
  ident: ref_73
  article-title: Therapeutic cell encapsulation techniques and applications in diabetes
  publication-title: Adv. Drug Deliv. Rev.
  doi: 10.1016/j.addr.2013.09.015
– volume: 197
  start-page: 251
  year: 2003
  ident: ref_102
  article-title: Studies on BrdU labeling of hematopoietic cells: Stem cells and cell lines
  publication-title: J. Cell. Physiol.
  doi: 10.1002/jcp.10357
– volume: 3
  start-page: 73
  year: 2016
  ident: ref_110
  article-title: Future challenges in the in vitro and in vivo evaluation of biomaterial biocompatibility
  publication-title: Regen. Biomater.
  doi: 10.1093/rb/rbw001
– volume: 2011
  start-page: 459251
  year: 2011
  ident: ref_126
  article-title: Inflammatory and angiogenic protein detection in the human vitreous: Cytometric bead assay
  publication-title: J. Ophthalmol.
  doi: 10.1155/2011/459251
– volume: 7
  start-page: 62
  year: 2010
  ident: ref_80
  article-title: The humanized NOD/SCID mouse as a preclinical model to study the fate of encapsulated human islets
  publication-title: Rev. Diabet. Stud.
  doi: 10.1900/RDS.2010.7.62
– volume: 132
  start-page: 76
  year: 2008
  ident: ref_71
  article-title: Cell microencapsulation technology: Towards clinical application
  publication-title: J. Control. Release
  doi: 10.1016/j.jconrel.2008.08.010
– volume: 8
  start-page: 25
  year: 2015
  ident: ref_77
  article-title: Islet Culture/Preservation Before Islet Transplantation
  publication-title: Cell Med
  doi: 10.3727/215517915X689047
– volume: 2
  start-page: 26
  year: 2014
  ident: ref_46
  article-title: Immunological and technical considerations in application of alginate-based microencapsulation systems
  publication-title: Front. Bioeng. Biotechnol.
– ident: ref_70
  doi: 10.1371/journal.pone.0091268
– volume: 33
  start-page: 1182
  year: 2016
  ident: ref_86
  article-title: The Influence of Stabilized Deconjugated Ursodeoxycholic Acid on Polymer-Hydrogel System of Transplantable NIT-1 Cells
  publication-title: Pharm. Res.
  doi: 10.1007/s11095-016-1863-y
– volume: 7
  start-page: 1683
  year: 2011
  ident: ref_38
  article-title: Biocompatibility and physicochemical characteristics of alginate–polycation microcapsules
  publication-title: Acta Biomater.
  doi: 10.1016/j.actbio.2010.12.006
– volume: 19
  start-page: 1523
  year: 2010
  ident: ref_76
  article-title: Pancreatic islet culture and preservation strategies: Advances, challenges, and future outlook
  publication-title: Cell Transplant.
  doi: 10.3727/096368910X515872
– volume: 22
  start-page: 1683
  year: 2006
  ident: ref_82
  article-title: Culture of neural stem cells in calcium alginate beads
  publication-title: Biotechnol. Prog.
  doi: 10.1002/bp060185z
– volume: 67–68
  start-page: 111
  year: 2014
  ident: ref_25
  article-title: Advances in biocompatibility and physico-chemical characterization of microspheres for cell encapsulation
  publication-title: Adv. Drug. Deliv. Rev.
  doi: 10.1016/j.addr.2013.07.010
– volume: 9
  start-page: 9281
  year: 2013
  ident: ref_50
  article-title: Ca(2+) released from calcium alginate gels can promote inflammatory responses in vitro and in vivo
  publication-title: Acta Biomater.
  doi: 10.1016/j.actbio.2013.08.002
– volume: 51
  start-page: 55
  year: 2002
  ident: ref_121
  article-title: Human pancreatic islets produce and secrete MCP-1/CCL2: Relevance in human islet transplantation
  publication-title: Diabetes
  doi: 10.2337/diabetes.51.1.55
– ident: ref_108
  doi: 10.1007/978-1-4614-4118-2
– volume: 73
  start-page: 116
  year: 2011
  ident: ref_97
  article-title: Estimation of Cell Proliferation Dynamics Using CFSE Data
  publication-title: Bull. Math. Biol.
  doi: 10.1007/s11538-010-9524-5
– ident: ref_132
  doi: 10.1371/journal.pone.0033023
– volume: 16
  start-page: 45
  year: 2014
  ident: ref_58
  article-title: Probucol Release from Novel Multicompartmental Microcapsules for the Oral Targeted Delivery in Type 2 Diabetes
  publication-title: AAPS PharmSciTech
  doi: 10.1208/s12249-014-0205-9
– volume: 83
  start-page: 1440
  year: 2007
  ident: ref_75
  article-title: Differentiation of transplanted microencapsulated fetal pancreatic cells
  publication-title: Transplantation
  doi: 10.1097/01.tp.0000264555.46417.7d
– volume: 9
  start-page: 10685
  year: 2019
  ident: ref_84
  article-title: Evaluation of cell viability and metabolic activity of a 3D cultured human epidermal model using a dynamic autoradiographic technique with a PET radiopharmaceutical
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-019-47153-0
– volume: 111
  start-page: A3.B.1
  year: 2015
  ident: ref_93
  article-title: Trypan Blue Exclusion Test of Cell Viability
  publication-title: Curr. Protoc. Immunol.
  doi: 10.1002/0471142735.ima03bs111
– ident: ref_39
  doi: 10.1371/journal.pone.0073498
– volume: 80
  start-page: 813
  year: 2007
  ident: ref_55
  article-title: Zeta-potentials of alginate-PLL capsules: A predictive measure for biocompatibility?
  publication-title: J. Biomed. Mater. Res. Part A
– volume: 6
  start-page: 2025
  year: 2018
  ident: ref_111
  article-title: Biocompatibility of polymer-based biomaterials and medical devices—Regulations, in vitro screening and risk-management
  publication-title: Biomater. Sci.
  doi: 10.1039/C8BM00518D
– volume: 3
  start-page: 39
  year: 2011
  ident: ref_44
  article-title: Differential scanning calorimetry: An invaluable tool for a detailed thermodynamic characterization of macromolecules and their interactions
  publication-title: J. Pharm. Bioallied. Sci.
  doi: 10.4103/0975-7406.76463
– ident: ref_87
– volume: 111
  start-page: 1
  year: 2009
  ident: ref_12
  article-title: Confocal microscopy study of polymer microcapsules for enzyme immobilisation in paper substrates
  publication-title: J. Appl. Polym. Sci.
  doi: 10.1002/app.28997
– volume: 8
  start-page: 874
  year: 2019
  ident: ref_63
  article-title: Convergence of Cell Pharmacology and Drug Delivery
  publication-title: STEM CELLS Transl. Med.
  doi: 10.1002/sctm.19-0019
– volume: 21
  start-page: 261
  year: 2010
  ident: ref_113
  article-title: Cytokine production by islets in health and diabetes: Cellular origin, regulation and function
  publication-title: Trends Endocrinol. Metab.
  doi: 10.1016/j.tem.2009.12.010
– volume: 67
  start-page: 172
  year: 2003
  ident: ref_34
  article-title: Fourier transform infrared spectroscopy studies of alginate-PLL capsules with varying compositions
  publication-title: J. Biomed. Mater. Res. A
– volume: 21
  start-page: 167
  year: 2010
  ident: ref_41
  article-title: Differential scanning calorimetry techniques: Applications in biology and nanoscience
  publication-title: J. Biomol. Tech. JBT
– volume: 19
  start-page: 8
  year: 2017
  ident: ref_94
  article-title: Cell Counting and Viability Assessment of 2D and 3D Cell Cultures: Expected Reliability of the Trypan Blue Assay
  publication-title: Biol. Proced. Online
  doi: 10.1186/s12575-017-0056-3
– volume: 60
  start-page: 124
  year: 2008
  ident: ref_117
  article-title: Challenges and emerging technologies in the immunoisolation of cells and tissues
  publication-title: Adv. Drug Deliv. Rev.
  doi: 10.1016/j.addr.2007.08.034
– volume: 40
  start-page: 631
  year: 2019
  ident: ref_61
  article-title: Pancreatic Islet Transplantation in Humans: Recent Progress and Future Directions
  publication-title: Endocr. Rev.
  doi: 10.1210/er.2018-00154
– volume: 67
  start-page: 679
  year: 2003
  ident: ref_74
  article-title: Effective removal of alginate-poly-L-lysine microcapsules from pancreatic islets by use of trypsin–EDTA
  publication-title: J. Biomed. Mater. Res. Part A
– volume: 25
  start-page: 503
  year: 2016
  ident: ref_109
  article-title: Characterization of Innate Immunity in an Extended Whole Blood Model of Human Islet Allotransplantation
  publication-title: Cell Transplant.
  doi: 10.3727/096368915X688461
– volume: 26
  start-page: 6950
  year: 2005
  ident: ref_37
  article-title: Physicochemical model of alginate–poly-L-lysine microcapsules defined at the micrometric/nanometric scale using ATR-FTIR, XPS, and ToF-SIMS
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2005.05.007
– volume: 44
  start-page: 1290
  year: 2015
  ident: ref_27
  article-title: Swelling, mechanical strength, and release properties of probucol microcapsules with and without a bile acid, and their potential oral delivery in diabetes
  publication-title: Artif. Cells Nanomed. Biotechnol.
  doi: 10.3109/21691401.2015.1024845
– volume: 35
  start-page: 141
  year: 2013
  ident: ref_30
  article-title: Is Scanning Electron Microscopy/Energy Dispersive X-ray Spectrometry (SEM/EDS) Quantitative?
  publication-title: Scanning
  doi: 10.1002/sca.21041
– volume: 59
  start-page: 508
  year: 2006
  ident: ref_60
  article-title: Polymer chemistry in diabetes treatment by encapsulated islets of Langerhans: Review to 2006
  publication-title: Aust. J. Chem.
  doi: 10.1071/CH06197
– volume: 31
  start-page: 308
  year: 2010
  ident: ref_123
  article-title: Anti-inflammatory peptide-functionalized hydrogels for insulin-secreting cell encapsulation
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2009.09.045
– ident: ref_7
– volume: 292
  start-page: C125
  year: 2007
  ident: ref_131
  article-title: Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells
  publication-title: Am. J. Physiol. Cell Physiol.
  doi: 10.1152/ajpcell.00247.2006
– volume: 82
  start-page: 386
  year: 2003
  ident: ref_11
  article-title: Visualization of alginate-poly-L-lysine-alginate microcapsules by confocal laser scanning microscopy
  publication-title: Biotechnol. Bioeng.
  doi: 10.1002/bit.10577
– volume: 13
  start-page: 1133
  year: 2016
  ident: ref_20
  article-title: Bile acids and bile acid derivatives: Use in drug delivery systems and as therapeutic agents
  publication-title: Expert Opin. Drug Deliv.
  doi: 10.1080/17425247.2016.1178233
– volume: 108
  start-page: 753
  year: 2018
  ident: ref_13
  article-title: Tracking the transdermal penetration pathways of optimized curcumin-loaded chitosan nanoparticles via confocal laser scanning microscopy
  publication-title: Int. J. Biol. Macromol.
  doi: 10.1016/j.ijbiomac.2017.10.170
– volume: 162
  start-page: 1996
  year: 2010
  ident: ref_90
  article-title: Monitoring of Cell Viability and Proliferation in Hydrogel-Encapsulated System by Resazurin Assay
  publication-title: Appl. Biochem. Biotechnol.
  doi: 10.1007/s12010-010-8975-3
– ident: ref_96
  doi: 10.3389/fphar.2020.00679
– volume: 15
  start-page: 804
  year: 2009
  ident: ref_19
  article-title: Bile acids: Chemistry, physiology, and pathophysiology
  publication-title: World J. Gastroenterol WJG
  doi: 10.3748/wjg.15.804
– volume: 62
  start-page: 1357
  year: 2013
  ident: ref_68
  article-title: Toward engineering a novel transplantation site for human pancreatic islets
  publication-title: Diabetes
  doi: 10.2337/db12-1553
– volume: 30
  start-page: 348
  year: 2009
  ident: ref_101
  article-title: Dose-dependent inhibition of BrdU detection in the cell proliferation ELISA by culture medium proteins
  publication-title: J. Immunoass. Immunochem.
  doi: 10.1080/15321810903084863
– volume: 9
  start-page: 25225
  year: 2019
  ident: ref_54
  article-title: Relation between the particle size and release characteristics of aromatic melamine microcapsules in functional textile applications
  publication-title: RSC Adv.
  doi: 10.1039/C9RA05196A
– volume: 77
  start-page: 587
  year: 2005
  ident: ref_116
  article-title: Inflammation-mediated dysfunction and apoptosis in pancreatic islet transplantation: Implications for intrahepatic grafts
  publication-title: J. Leukoc. Biol.
  doi: 10.1189/jlb.1104649
– volume: 435
  start-page: 297
  year: 2011
  ident: ref_133
  article-title: Assessing mitochondrial dysfunction in cells
  publication-title: Biochem. J.
  doi: 10.1042/BJ20110162
– volume: 32
  start-page: 151
  year: 2015
  ident: ref_45
  article-title: Release and swelling studies of an innovative antidiabetic-bile acid microencapsulated formulation, as a novel targeted therapy for diabetes treatment
  publication-title: J. Microencapsul.
  doi: 10.3109/02652048.2014.958204
– volume: 7
  start-page: 63
  year: 2019
  ident: ref_31
  article-title: The application of FTIR microspectroscopy in a non-invasive and non-destructive way to the study and conservation of mineralised excavated textiles
  publication-title: Herit. Sci.
  doi: 10.1186/s40494-019-0304-8
– ident: ref_16
  doi: 10.1371/journal.pone.0234125
– volume: 11
  start-page: 65
  year: 2018
  ident: ref_95
  article-title: Influence of Biotechnological Processes, Speed of Formulation Flow and Cellular Concurrent Stream-Integration on Insulin Production from β-cells as a Result of Co-Encapsulation with a Highly Lipophilic Bile Acid
  publication-title: Cell Mol. Bioeng.
  doi: 10.1007/s12195-017-0510-y
– volume: 44
  start-page: 588
  year: 2014
  ident: ref_5
  article-title: Advanced bile acid-based multi-compartmental microencapsulated pancreatic beta-cells integrating a polyelectrolyte-bile acid formulation, for diabetes treatment
  publication-title: Artif. Cells Nanomed. Biotechnol.
  doi: 10.3109/21691401.2014.971806
– volume: 29
  start-page: 986
  year: 2013
  ident: ref_91
  article-title: Use of the mitochondria toxicity assay for quantifying the viable cell density of microencapsulated jurkat cells
  publication-title: Biotechnol. Prog.
  doi: 10.1002/btpr.1734
– ident: ref_79
  doi: 10.1371/journal.pone.0040868
– volume: 10
  start-page: 4362
  year: 2020
  ident: ref_36
  article-title: Pancreatic islets seeded in a novel bioscaffold forms an organoid to rescue insulin production and reverse hyperglycemia in models of type 1 diabetes
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-020-60947-x
– volume: 83
  start-page: 216
  year: 2007
  ident: ref_10
  article-title: Formulating the alginate-polyornithine biocapsule for prolonged stability: Evaluation of composition and manufacturing technique
  publication-title: J. Biomed. Mater. Res. A
  doi: 10.1002/jbm.a.31472
– volume: 12
  start-page: 1143
  year: 2006
  ident: ref_128
  article-title: Application of multiplex cytometric bead array technology for the measurement of angiogenic factors in the vitreous
  publication-title: Mol. Vis.
– volume: 7
  start-page: 10059
  year: 2017
  ident: ref_106
  article-title: Co-encapsulation and co-transplantation of mesenchymal stem cells reduces pericapsular fibrosis and improves encapsulated islet survival and function when allografted
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-017-10359-1
– volume: 67–68
  start-page: 35
  year: 2013
  ident: ref_72
  article-title: Encapsulated islets for diabetes therapy: History, current progress, and critical issues requiring solution
  publication-title: Adv. Drug Deliv. Rev.
– volume: 136
  start-page: 153
  year: 2012
  ident: ref_127
  article-title: Bile acids induce monocyte differentiation toward interleukin-12 hypo-producing dendritic cells via a TGR5-dependent pathway
  publication-title: Immunology
  doi: 10.1111/j.1365-2567.2012.03554.x
– volume: 4
  start-page: 22041
  year: 2019
  ident: ref_40
  article-title: Combined Use of Scanning Electron Microscopy–Energy-Dispersive X-ray Spectroscopy and Fourier Transform Infrared Imaging Coupled with Principal Component Analysis in the Study of Ancient Egyptian Papyri
  publication-title: ACS Omega
  doi: 10.1021/acsomega.9b03145
– ident: ref_88
  doi: 10.1371/journal.pone.0231634
– volume: 8
  start-page: 665
  year: 2020
  ident: ref_125
  article-title: Modulating Alginate Hydrogels for Improved Biological Performance as Cellular 3D Microenvironments
  publication-title: Front. Bioeng. Biotechnol.
  doi: 10.3389/fbioe.2020.00665
– volume: 56
  start-page: 1458
  year: 2013
  ident: ref_130
  article-title: Islet encapsulation: Advances and obstacles
  publication-title: Diabetologia
  doi: 10.1007/s00125-013-2921-1
– volume: 8
  start-page: 1221
  year: 2014
  ident: ref_24
  article-title: Microencapsulation as a novel delivery method for the potential antidiabetic drug, Probucol
  publication-title: Des. Dev. Ther.
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Snippet The utilisation of bioartificial organs is of significant interest to many due to their versatility in treating a wide range of disorders. Microencapsulation...
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StartPage 1861
SubjectTerms Acids
Artificial organs
Bile
bioartificial organ
Biocompatibility
Biotechnology
cell microencapsulation
Fourier transforms
Hydrogels
immunogenic considerations
Immunogenicity
in vitro testing
microcapsule analysis
Microcapsules
Microencapsulation
Morphology
Pancreas
Permeability
Polymers
Review
Scanning electron microscopy
Spectrum analysis
Tissue engineering
Topography
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Title Advancements in Assessments of Bio-Tissue Engineering and Viable Cell Delivery Matrices Using Bile Acid-Based Pharmacological Biotechnologies
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