Optimization of an accelerator-based epithermal neutron source for neutron capture therapy

A modeling investigation was performed to choose moderator material and size for creating optimal epithermal neutron beams for BNCT based on a proton accelerator and the 7Li(p,n) 7Be reaction as a neutrons source. An optimal configuration is suggested for the beam shaping assembly made from polytetr...

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Bibliographic Details
Published inApplied radiation and isotopes Vol. 61; no. 5; pp. 1009 - 1013
Main Authors Kononov, O.E, Kononov, V.N, Bokhovko, M.V, Korobeynikov, V.V, Soloviev, A.N, Sysoev, A.S, Gulidov, I.A, Chu, W.T, Nigg, D.W
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.11.2004
Subjects
Accelerator
Boron Neutron Capture Therapy - instrumentation
Boron Neutron Capture Therapy - statistics & numerical data
Computer Simulation
Epithermal neutrons
Facility Design and Construction
Fast Neutrons - therapeutic use
Humans
Monte Carlo Method
Neoplasms - radiotherapy
Neutron capture therapy
Neutron moderation
Particle Accelerators
Phantoms, Imaging
Radiotherapy Dosage
Neutron capture therapy
Epithermal neutrons
Neutron moderation
Accelerator
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Summary:A modeling investigation was performed to choose moderator material and size for creating optimal epithermal neutron beams for BNCT based on a proton accelerator and the 7Li(p,n) 7Be reaction as a neutrons source. An optimal configuration is suggested for the beam shaping assembly made from polytetrafluoroethylene and magnesium fluorine to be placed on high current IPPE proton accelerator KG-2.5. Results of calculation were experimentally tested and are in good agreement with measurements.
Bibliography:ObjectType-Article-1
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ISSN:0969-8043
1872-9800
DOI:10.1016/j.apradiso.2004.05.028