Management of Acute Kidney Injury in Pregnancy for the Obstetrician

• Published in: Obstetrics and gynecology clinics of North America Vol. 43; no. 4; p. 747
• Main Author: Acharya, Anjali
• Format: Journal Article
• Language: English
• Published: United States 01.12.2016
• Subjects: Acute Kidney Injury - diagnosis; Acute Kidney Injury - etiology; Acute Kidney Injury - physiopathology; Acute Kidney Injury - therapy; Female; Humans; Incidence; Kidney Function Tests - methods; Pregnancy; Pregnancy Complications - diagnosis; Pregnancy Complications - etiology; Pregnancy Complications - physiopathology; Pregnancy Complications - therapy; Pregnancy Outcome; Renal Replacement Therapy - methods; Risk Factors; Severity of Illness Index; Atypical hemolytic uremic syndrome; Thrombotic microangiopathy; Pregnancy-related acute kidney injury; Acute kidney injury; Preeclampsia; Hypertensive disorders of pregnancy
• ISSN: 1558-0474
• DOI: 10.1016/j.ogc.2016.07.007

Acute kidney injury (AKI) is a complex disorder that occurs in several clinical settings. During pregnancy, there are additional unique conditions that contribute to AKI. The clinical manifestations of AKI during pregnancy range from a minimal elevation in serum creatinine to renal failure requiring renal replacement therapy, similar to AKI in the general population. Recent epidemiologic studies in the general population show an increase in mortality associated with AKI, particularly when dialysis is required. The incidence of AKI in pregnancy remains a cause of significant morbidity and mortality.