The Pathomechanism, Antioxidant Biomarkers, and Treatment of Oxidative Stress-Related Eye Diseases

• Published in: International journal of molecular sciences Vol. 23; no. 3; p. 1255
• Main Authors: Hsueh, Yi-Jen, Chen, Yen-Ning, Tsao, Yu-Ting, Cheng, Chao-Min, Wu, Wei-Chi, Chen, Hung-Chi
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 23.01.2022; MDPI
• Subjects: Aging; Angiogenesis; Antioxidants; Antioxidants - metabolism; Apoptosis; Autophagy; Biomarkers; Cataract - pathology; Cornea; DNA damage; Enzymes; Eye - metabolism; Eye diseases; Eye Diseases - pathology; Eye Diseases - therapy; Free radicals; Gene expression; Glaucoma - pathology; Humans; Inflammation; Lens, Crystalline - metabolism; Lipid peroxidation; Lipids; Macular Degeneration - pathology; Mitochondrial DNA; Oxidation; Oxidation-Reduction; Oxidative stress; Oxidative Stress - physiology; Pathogenesis; Proteins; Reactive Oxygen Species; Review; Signal transduction; Uric acid; Vascular endothelial growth factor; antioxidant biomarkers; antioxidant therapy; oxidative stress; ocular diseases

Oxidative stress is an important pathomechanism found in numerous ocular degenerative diseases. To provide a better understanding of the mechanism and treatment of oxidant/antioxidant imbalance-induced ocular diseases, this article summarizes and provides updates on the relevant research. We review...