A boy with membranous nephropathy after allogeneic bone marrow transplantation

A 6-year-old boy developed bronchiolitis obliterans organizing pneumonia and nephrotic syndrome 5 months after allogeneic bone marrow transplantation from an unrelated donor for acute lymphoblastic leukemia. His renal biopsy showed membranous nephropathy. He was treated with prednisolone and cyclosp...

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Published inClinical and experimental nephrology Vol. 13; no. 5; pp. 508 - 511
Main Authors Motoyama, Osamu, Uchino, Yumiko, Tokuyama, Mika, Iitaka, Kikuo, Ohara, Akira
Format Journal Article
LanguageEnglish
Published Tokyo Springer Japan 01.10.2009
Springer Nature B.V
Subjects
Bone Marrow Transplantation - adverse effects
Case Report
Child, Preschool
Glomerulonephritis, Membranous - etiology
Hematopoietic Stem Cell Transplantation - adverse effects
Humans
Kidney Glomerulus - pathology
Male
Medicine
Medicine & Public Health
Nephrology
Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy
Transplantation, Homologous - adverse effects
Urology
Graft-versus-host disease
Bone marrow transplantation
Nephrotic syndrome
Membranous nephropathy
Hematopoietic stem cell transplantation
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Summary:A 6-year-old boy developed bronchiolitis obliterans organizing pneumonia and nephrotic syndrome 5 months after allogeneic bone marrow transplantation from an unrelated donor for acute lymphoblastic leukemia. His renal biopsy showed membranous nephropathy. He was treated with prednisolone and cyclosporine A. Proteinuria disappeared 3 months after the onset of nephrotic syndrome. To our knowledge, this patient is the youngest case with nephrotic syndrome due to membranous nephropathy after hematopoietic stem cell transplantation.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
ObjectType-Article-3
ISSN:1342-1751
1437-7799
DOI:10.1007/s10157-009-0178-2