Factors predicting post-stroke aphasia recovery

Abstract Background Aphasia is an important stroke sequel that impacts negatively on the HQoL of stroke patients. Although a number of stroke patients with aphasia will have good functional recovery, many are left with language deficits. Method Papers were identified through PubMed and MEDLINE searc...

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Published inJournal of the neurological sciences Vol. 352; no. 1; pp. 12 - 18
Main Authors Watila, Musa Mamman, Balarabe, Salisu Abdullahi
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 15.05.2015
Subjects
Aphasia
Aphasia - etiology
Aphasia - physiopathology
Brain - pathology
Humans
Language
Neurology
Neuroplasticity
Predictors
Prognosis
Recovery
Recovery of Function
Severity of Illness Index
Stroke
Stroke - complications
Stroke - pathology
Stroke - physiopathology
Neuroplasticity
Aphasia
Stroke
Language
Recovery
Predictors
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Summary:Abstract Background Aphasia is an important stroke sequel that impacts negatively on the HQoL of stroke patients. Although a number of stroke patients with aphasia will have good functional recovery, many are left with language deficits. Method Papers were identified through PubMed and MEDLINE search, with keywords such as: ‘stroke’, ‘aphasia’, ‘post-stroke aphasia’, ‘factors that predict aphasia recovery’, ‘aphasia outcomes’ and ‘aphasia prognosis’. Results The most important factors that determine recovery are the lesion location and size, aphasia type and severity and to some extent the nature of early haemodynamic response, and treatment received. Anagraphic factors like gender, age, handedness and education have not been found to be robust predictors of recovery. Conclusions Predicting post-stroke aphasia recovery is difficult, because of the interplay between lesion, anagraphic, and treatment-related factors, in addition to the role of neuroplasticity.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:0022-510X
1878-5883
DOI:10.1016/j.jns.2015.03.020