The antileukoprotease secretory leukocyte protease inhibitor (SLPI) and its role in the prevention of HPV-infections in head and neck squamous cell carcinoma
Highlights • The data confirm the association between SLPI/annexin A2, Smoking and HPV-infection. • Worldwide first investigation of this kind. • The HNSCC patient cohort represents the largest tested for these parameters ever. • Smoking induced SLPI expression protects from HPV infections. • Non-sm...
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Published in | Cancer letters Vol. 357; no. 1; pp. 339 - 345 |
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Main Authors | , , , , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Ireland
Elsevier B.V
01.02.2015
Elsevier Limited |
Subjects | |
Online Access | Get full text |
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Summary: | Highlights • The data confirm the association between SLPI/annexin A2, Smoking and HPV-infection. • Worldwide first investigation of this kind. • The HNSCC patient cohort represents the largest tested for these parameters ever. • Smoking induced SLPI expression protects from HPV infections. • Non-smokers are at risk of successful HPV infections due to low SLPI levels. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0304-3835 1872-7980 |
DOI: | 10.1016/j.canlet.2014.11.043 |