Supernumerary minute ring chromosome 14 in a man with primary infertility and left varicocele
Objective To describe a case of supernumerary minute ring chromosome (SMRC) in an infertile man, with the concurrent finding of a left varicocele. Design Case report. Setting Urologic infertility clinic in a university hospital. Patient(s) Male patient presenting with primary infertility. Interventi...
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Published in | Fertility and sterility Vol. 87; no. 5; pp. 1213.e1 - 1213.e3 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Elsevier Inc
01.05.2007
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Subjects | |
Online Access | Get full text |
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Summary: | Objective To describe a case of supernumerary minute ring chromosome (SMRC) in an infertile man, with the concurrent finding of a left varicocele. Design Case report. Setting Urologic infertility clinic in a university hospital. Patient(s) Male patient presenting with primary infertility. Intervention(s) Karyotyping, genetic counseling, and microsurgical left varicocelectomy. Main Outcome Measure(s) Sperm concentration and motility, chromosomal number and structure. Result(s) Fluorescence in situ hybridization revealing SMRC 14. Sperm concentration and motility improved after left varicocele repair. Conclusion(s) A karyotype should be included in the evaluation of severe oligospermia. Although SMRC 14 may be associated with fertility problems, repair of a coexisting varicocele should be considered in these patients. |
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Bibliography: | ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3 |
ISSN: | 0015-0282 1556-5653 |
DOI: | 10.1016/j.fertnstert.2006.09.008 |