AVIA v2.0: annotation, visualization and impact analysis of genomic variants and genes

As sequencing becomes cheaper and more widely available, there is a greater need to quickly and effectively analyze large-scale genomic data. While the functionality of AVIA v1.0, whose implementation was based on ANNOVAR, was comparable with other annotation web servers, AVIA v2.0 represents an enh...

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Bibliographic Details
Published inBioinformatics Vol. 31; no. 16; pp. 2748 - 2750
Main Authors Vuong, Hue, Che, Anney, Ravichandran, Sarangan, Luke, Brian T, Collins, Jack R, Mudunuri, Uma S
Format Journal Article
LanguageEnglish
Published England Oxford University Press 15.08.2015
Subjects
Annotations
Applications Notes
Bioinformatics
Databases, Genetic
Genes
Genetic Variation
Impact analysis
Internet
Molecular Sequence Annotation
Sequencing
Servers
Servers (computers)
Software
World Wide Web
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Summary:As sequencing becomes cheaper and more widely available, there is a greater need to quickly and effectively analyze large-scale genomic data. While the functionality of AVIA v1.0, whose implementation was based on ANNOVAR, was comparable with other annotation web servers, AVIA v2.0 represents an enhanced web-based server that extends genomic annotations to cell-specific transcripts and protein-level functional annotations. With AVIA's improved interface, users can better visualize their data, perform comprehensive searches and categorize both coding and non-coding variants. AVIA is freely available through the web at http://avia.abcc.ncifcrf.gov. Hue.Vuong@fnlcr.nih.gov Supplementary data are available at Bioinformatics online.
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Associate Editor: John Hancock
ISSN:1367-4803
1367-4811
1460-2059
DOI:10.1093/bioinformatics/btv200