Association between urban–rural location and prevalence of type 2 diabetes and impaired fasting glucose in West Africa: a cross–sectional population–based epidemiological study

• Published in: BMJ open Vol. 13; no. 9; p. e063318
• Main Authors: Issaka, Ayuba, Stevenson, Christopher, Paradies, Yin, Houehanou, Yessito Corine N, Bosu, William K, Kiwallo, Jean Baptiste, Wesseh, Chea Sanford, Houinato, Dismand Stephan, Nazoum, Diarra J P, Cameron, Adrian J
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group LTD 21.09.2023; BMJ Publishing Group
• Series: Original research
• Subjects: Alcohol; Blood pressure; Body mass index; Cardiovascular Medicine; Diabetes; Epidemiology; Fasting; Glucose; Marital status; Obesity; Population-based studies; Risk factors; Rural areas; Sensitivity analysis; Sociodemographics; Surveillance; Urban areas; Urbanization; Variables; Ghana; Burkina Faso; West Africa; Africa
• ISSN: 2044-6055; 2044-6055
• DOI: 10.1136/bmjopen-2022-063318

Objectives We investigated the association between urban/rural location and both type 2 diabetes mellitus (T2DM) and pre-diabetes among populations of five West African countries. Design Cross-sectional studies, using the WHO Stepwise (STEPs) survey data. Setting National representative data of both urban and rural areas from Benin, Burkina Faso, Ghana, Liberia and Mali. Participants Adults comprising 15 468 participants (6774 men and 8746 women; 7663 urban and 7805 rural residents) aged between 25 and 64 years. Results The age and sex-adjusted prevalence of T2DM was 6.2% for urban areas and 2.5% for rural areas. The prevalence of impaired fasting glucose (IFG) was 6.6% for urban areas, and 3.0% for rural areas. No differences by sex were observed. The crude relative risk (RR) and 95% CI of T2DM and IFG in urban compared with rural areas were 2.69 (1.85 to 3.91) and 2.37 (1.53 to 3.66), respectively. This reduced to RR: 2.03, 95% CI (1.34 to 3.08) and RR: 2.04, 95% CI (1.27 to 3.28), respectively, after adjusting for covariables. Conclusion The prevalence of both T2DM and IFG was more than two times as high in urban areas compared with rural areas in West Africa. Behavioural risk factors are common among urban populations, with ongoing urbanisation expected to drive increases in the prevalence of T2DM. These results could guide planning for T2DM screening, preventive strategies and resource allocation in West Africa.