Group A streptococcal vaccines: Paving a path for accelerated development

Highlights ► We summarize the global burden of group A streptococcal diseases. ► We review the current status of group A streptococcal vaccines. ► We describe obstacles to streptococcal vaccine development. ► We detail a path for accelerated vaccine development. ► Cooperation and collaboration are k...

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Published inVaccine Vol. 31; pp. B216 - B222
Main Authors Dale, James B, Fischetti, Vincent A, Carapetis, Jonathan R, Steer, Andrew C, Sow, Samba, Kumar, Rajesh, Mayosi, Bongani M, Rubin, Fran A, Mulholland, Kim, Hombach, Joachim Maria, Schödel, Florian, Henao-Restrepo, Ana Maria
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Ltd 18.04.2013
Subjects
Allergy and Immunology
antigens
Antigens, Bacterial - immunology
Autoimmunity
Bacterial Outer Membrane Proteins - immunology
Biomedical Research - trends
Carrier Proteins - immunology
Cost of Illness
fever
glomerulonephritis
Group A streptococci
heart diseases
Humans
Molecular Epidemiology
morbidity
mortality
pharyngitis
Rheumatic heart disease
selection criteria
Streptococcal Infections - prevention & control
Streptococcal Vaccines - therapeutic use
Streptococcus
Streptococcus pyogenes
vaccine development
Vaccines
Group A streptococci
Vaccines
Rheumatic heart disease
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Summary:Highlights ► We summarize the global burden of group A streptococcal diseases. ► We review the current status of group A streptococcal vaccines. ► We describe obstacles to streptococcal vaccine development. ► We detail a path for accelerated vaccine development. ► Cooperation and collaboration are keys to success.
Bibliography:http://dx.doi.org/10.1016/j.vaccine.2012.09.045
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ObjectType-Feature-1
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2012.09.045