Subtyping of Panic Disorder by Symptom Profile

During Phase II of the Cross-National Panic Study, descriptions of the patient's last severe panic attack were collected for 1168 patients. Statistical analysis indicated that patients could be divided into two groups, characterised by the presence or absence of prominent respiratory symptoms....

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Bibliographic Details
Published inBritish journal of psychiatry Vol. 163; no. 2; pp. 201 - 209
Main Authors Briggs, Andrew C., Stretch, David D., Brandon, Sydney
Format Journal Article
LanguageEnglish
Published Cambridge, UK Cambridge University Press 01.08.1993
RCP
Subjects
Adult
Alprazolam
Alprazolam - therapeutic use
Anxiety
Colombia - epidemiology
Europe - epidemiology
Female
Humans
Imipramine
Imipramine - therapeutic use
Interview, Psychological
Linear Models
Male
Mexico - epidemiology
Middle Aged
Panic attacks
Panic Disorder - classification
Panic Disorder - drug therapy
Panic Disorder - epidemiology
Panic Disorder - physiopathology
Panic disorders
Psychopathology
Respiration Disorders - psychology
Statistical analysis
United States - epidemiology
Colombia
Mexico
United States
Europe
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Summary:During Phase II of the Cross-National Panic Study, descriptions of the patient's last severe panic attack were collected for 1168 patients. Statistical analysis indicated that patients could be divided into two groups, characterised by the presence or absence of prominent respiratory symptoms. The two groups did not differ on demographic variables or coexisting diagnoses, but they did differ on psychopathology on entry to the study and treatment outcome. The group with prominent respiratory symptoms suffered more spontaneous panic attacks and responded to imipramine, whereas the group without prominent respiratory symptoms suffered more situational panic attacks and responded more to alprazolam. It is important to distinguish spontaneous and situational panic attacks, to aid choice of treatment.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
ObjectType-News-3
content type line 23
ISSN:0007-1250
1472-1465
DOI:10.1192/bjp.163.2.201