Mice immunized with bone marrow-derived dendritic cells stimulated with recombinant Coxiella burnetii Com1 and Mip demonstrate enhanced bacterial clearance in association with a Th1 immune response
Highlights ► Recombinant proteins Com1, Mip and GroEL were cloned and used to stimulate BMDCs. ► Mice receiving Com1 or Mip-pulsed DCs showed lower bacterial loads than control. ► Mice receiving Com1 or Mip-pulsed DCs exhibited greater IFN-γ-positive cells.
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Published in | Vaccine Vol. 30; no. 48; pp. 6809 - 6815 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
Netherlands
Elsevier Ltd
06.11.2012
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Subjects | |
Online Access | Get full text |
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Summary: | Highlights ► Recombinant proteins Com1, Mip and GroEL were cloned and used to stimulate BMDCs. ► Mice receiving Com1 or Mip-pulsed DCs showed lower bacterial loads than control. ► Mice receiving Com1 or Mip-pulsed DCs exhibited greater IFN-γ-positive cells. |
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Bibliography: | http://dx.doi.org/10.1016/j.vaccine.2012.09.017 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Article-2 ObjectType-Feature-1 |
ISSN: | 0264-410X 1873-2518 |
DOI: | 10.1016/j.vaccine.2012.09.017 |