Decisions about deep brain stimulation therapy in Parkinson's disease

• Published in: Arquivos de neuro-psiquiatria Vol. 76; no. 6; pp. 411 - 420
• Main Authors: Brandão, Pedro, Grippe, Talyta Cortez, Modesto, Luiz Cláudio, Ferreira, André Gustavo Fonseca, Silva, Flávia Martins da, Pereira, Flávio Faria, Lobo, Marcelo Evangelista, Allam, Nasser, Freitas, Tiago da Silva, Munhoz, Renato P
• Format: Journal Article
• Language: English; Portuguese
• Published: Brazil Arquivos de Neuro-Psiquiatria 01.06.2018; Academia Brasileira de Neurologia - ABNEURO; Academia Brasileira de Neurologia (ABNEURO)
• Subjects: basal ganglia; Clinical Decision-Making; Deep brain stimulation; Deep Brain Stimulation - methods; Globus pallidus; Humans; NEUROSCIENCES; neurosurgical procedures; Parkinson disease; Parkinson Disease - therapy; PSYCHIATRY; reference standards; Subthalamic nucleus; Tremor; gânglios da base; neurosurgical procedures; basal ganglia; doença de Parkinson; Parkinson disease; procedimentos neurocirúrgicos; reference standards; deep brain stimulation; padrões de referência; estimulação cerebral profunda
• ISSN: 0004-282X; 1678-4227; 1678-4227
• DOI: 10.1590/0004-282X20180048

Parkinson's disease can be treated surgically in patients who present with motor complications such as fluctuations and dyskinesias, or medically-refractory disabling tremor. In this review, a group of specialists formulated suggestions for a preoperative evaluation protocol after reviewing the literature published up to October 2017. In this protocol, eligibility and ineligibility criteria for surgical treatment were suggested, as well as procedures that should be carried out before the multidisciplinary therapeutic decisions. The review emphasizes the need to establish "DBS teams", with professionals dedicated specifically to this area. Finally, surgical target selection (subthalamic nucleus or globus pallidus internus) is discussed briefly, weighing the pros and cons of each target.