Inflammatory Myofibroblastic Tumor Mimicking Apical Periodontitis

• Published in: Journal of endodontics Vol. 41; no. 12; pp. 2079 - 2082
• Main Authors: Adachi, Makoto, DDS, PhD, Kiho, Kazuki, DDS, Sekine, Genta, DDS, PhD, Ohta, Takahisa, DDS, PhD, Matsubara, Makoto, DDS, PhD, Yoshida, Takakazu, DDS, PhD, Katsumata, Akitoshi, DDS, PhD, Tanuma, Jun-ichi, DDS, PhD, Sumitomo, Shinichiro, DDS, PhD
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.12.2015
• Subjects: Adult; Apical periodontitis; Cone-Beam Computed Tomography; Dentistry; Diagnosis, Differential; Endocrinology & Metabolism; Humans; inflammatory myofibroblastic tumor; Jaw Neoplasms - diagnostic imaging; Jaw Neoplasms - pathology; Jaw Neoplasms - surgery; jaw tumor; Magnetic Resonance Imaging; Male; mandible; Neoplasms, Muscle Tissue - diagnostic imaging; Neoplasms, Muscle Tissue - pathology; Neoplasms, Muscle Tissue - surgery; Periapical Periodontitis - diagnosis; Radiography, Panoramic; mandible; Apical periodontitis; jaw tumor; inflammatory myofibroblastic tumor
• ISSN: 0099-2399; 1878-3554
• DOI: 10.1016/j.joen.2015.09.006

Abstract Inflammatory myofibroblastic tumors (IMTs) are rare. IMTs of the head and neck occur in all age groups, from neonates to old age, with the highest incidence occurring in childhood and early adulthood. An IMT has been defined as a histologically distinctive lesion of uncertain behavior. This article describes an unusual case of IMT mimicking apical periodontitis in the mandible of a 42-year-old man. At first presentation, the patient showed spontaneous pain and percussion pain at teeth #28 to 30, which continued after initial endodontic treatment. Panoramic radiography revealed a radiolucent lesion at the site. Cone-beam computed tomographic imaging showed osteolytic lesions, suggesting an aggressive neoplasm requiring incisional biopsy. Histopathological examination indicated an IMT. The lesion was removed en bloc under general anesthesia, and the patient manifested no clinical evidence of recurrence for 24 months. Lesions of nonendodontic origin should be included in the differential diagnosis of apical periodontitis. Every available diagnostic tool should be used to confirm the diagnosis. Cone-beam computed tomographic imaging is very helpful for differential diagnosis in IMTs mimicking apical periodontitis.