Plugging the Leaks

The identification of the claudin family of membrane proteins is discussed. Although this discovery adds much to the study of the regulation of epithelial permeability, a complete catalogue of the protein players may still be incomplete.

Saved in:
Bibliographic Details
Published inProceedings of the National Academy of Sciences - PNAS Vol. 96; no. 2; pp. 319 - 321
Main Author Goodenough, Daniel A.
Format Journal Article
LanguageEnglish
Published United States National Academy of Sciences of the United States of America 19.01.1999
National Acad Sciences
National Academy of Sciences
The National Academy of Sciences
Subjects
Animals
Bone fractures
Cell lines
Cell Membrane - physiology
Cell Membrane Permeability - physiology
Cells
Commentary
Cytoplasm
Epithelial cells
Epithelial Cells - physiology
Epithelium
Membrane Proteins - chemistry
Membranes
Microscopy, Electron
Models, Biological
Molecules
Permeability
Physiological regulation
Proteins
Tight junctions
Tight Junctions - chemistry
Tight Junctions - ultrastructure
Vertebrates
Online AccessGet full text

Cover

More Information
Summary:The identification of the claudin family of membrane proteins is discussed. Although this discovery adds much to the study of the regulation of epithelial permeability, a complete catalogue of the protein players may still be incomplete.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
To whom reprint requests should be addressed. e-mail: daniel_goodenough@hms.harvard.edu.
ISSN:0027-8424
1091-6490
DOI:10.1073/pnas.96.2.319