Unique Characteristics and Failure Patterns of Metaplastic Breast Cancer in Contrast to Invasive Ductal Carcinoma: A Retrospective Multicenter Case–Control Study (KROG 13-07)

• Published in: Clinical breast cancer Vol. 15; no. 2; pp. e105 - e115
• Main Authors: Yu, Jeong Il, Choi, Doo Ho, Huh, Seung Jae, Ahn, Sung Ja, Lee, Ji Shin, Shin, Kyung Hwan, Kwon, Youngmee, Kim, Yong Bae, Suh, Chang-Ok, Kim, Jin Hee, Cho, Jihyoung, Kim, In Ah, Lee, Jong Hoon, Park, Won
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.04.2015
• Subjects: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor - analysis; Breast Neoplasms - mortality; Breast Neoplasms - pathology; Carcinoma, Ductal, Breast - mortality; Carcinoma, Ductal, Breast - pathology; Case-Control Studies; Case-control study; Female; Hematology, Oncology and Palliative Medicine; Humans; Immunohistochemistry; Invasive ductal carcinoma; Kaplan-Meier Estimate; Metaplasia; Metaplastic breast cancer; Middle Aged; Neoplasm Recurrence, Local - mortality; Obstetrics and Gynecology; Pattern of failure; Prognosis; Prognostic factor; Retrospective Studies; Risk Factors; Triple Negative Breast Neoplasms - mortality; Triple Negative Breast Neoplasms - pathology; Young Adult; Prognostic factor; Case-control study; Invasive ductal carcinoma; Pattern of failure; Metaplastic breast cancer
• ISSN: 1526-8209; 1938-0666
• DOI: 10.1016/j.clbc.2014.10.002

Micro-Abstract In this retrospective multicenter study, a comparison of metaplastic breast cancer (MBC) patients with exactly matched patients with invasive ductal carcinoma (IDC) showed that MBC is associated with a greater incidence of triple negativity, poor differentiation, and a greater recurrence rate. The locoregional and systemic management might be modified in MBC.