Ferroptosis-Related Gene SLC1A5 Is a Novel Prognostic Biomarker and Correlates with Immune Microenvironment in HBV-Related HCC

• Published in: Journal of clinical medicine Vol. 12; no. 5; p. 1715
• Main Authors: Su, Hanwen, Liu, Youyi, Huang, Jingtao
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 21.02.2023; MDPI
• Subjects: Biological markers; Biomarkers; Cancer; Cell death; Clinical medicine; Complications and side effects; Development and progression; Disease; Ferroptosis; Gene expression; Genetic aspects; Health aspects; Hepatitis B; Hepatitis C; Hepatoma; Infections; Liver cancer; Medical prognosis; Oncology, Experimental; Pathogenesis; Prognosis; Regression analysis; Risk factors; Software; Survival analysis; China; HCC; ferroptosis-related gene; SLC1A5; tumor microenvironment; HBV

(1) Background: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide with limited treatment satisfaction. Finding new therapeutic targets has remained a major challenge. Ferroptosis is an iron-dependent cell death program that plays a regulatory role in HBV infection and HCC de...