Right Atrial Volume Is Superior to Left Atrial Volume for Prediction of Atrial Fibrillation Recurrence After Direct Current Cardioversion

• Published in: Canadian journal of cardiology Vol. 31; no. 1; pp. 29 - 35
• Main Authors: Luong, Christina, MD, Thompson, Darby J.S., PhD, Bennett, Matthew, MD, Gin, Kenneth, MD, Jue, John, MD, Barnes, Marion E., MSc, Colley, Pamela, MN, NP, Tsang, Teresa S.M., MD
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 2015
• Subjects: Aged; Atrial Fibrillation - diagnostic imaging; Atrial Fibrillation - physiopathology; Atrial Fibrillation - therapy; Atrial Function, Left - physiology; Cardiovascular; Echocardiography - methods; Electric Countershock; Electrocardiography; Female; Follow-Up Studies; Heart Atria - diagnostic imaging; Heart Atria - physiopathology; Humans; Male; Middle Aged; Prognosis; Recurrence; Time Factors
• ISSN: 0828-282X; 1916-7075
• DOI: 10.1016/j.cjca.2014.10.009

Abstract Background The value of right atrial volume as a predictor for recurrence of atrial fibrillation (AF) after direct current cardioversion (DCCV) is unknown. Methods We sought to compare the performance of right atrial volume indexed to body surface area (RAVI), left atrial diameter, left atrial volume indexed to body surface area (LAVI), and biatrial volume index (BAVI) for the prediction of AF recurrence at 6 months after DCCV. This study included the first 95 consecutive patients from the AF Clinic at a large tertiary care hospital who underwent DCCV and who had an echocardiogram available within 6 months before DCCV. Maximal LAVI, RAVI, and BAVI were determined from the echocardiogram before DCCV. Electrocardiographic and clinical data were acquired at baseline, before cardioversion, and at each clinic visit. Results Of the 95 patients (64 male; mean age, 63 ± 12 years), history of systemic hypertension, diabetes mellitus, heart failure, and transient ischemic attack/stroke was present in 60 (63%), 14 (15%), 27 (28%), and 5 (5%) patients, respectively. Mean duration from AF diagnosis to DCCV was 3.5 ± 5.0 years. At 6 months after DCCV, 53 (56%) had reverted to AF. RAVI had superior predictive ability (area under the receiver operator characteristic curve: RAVI, 0.77; left atrial diameter, 0.54; LAVI, 0.64; and BAVI, 0.70). RAVI ≥ 42 mL/m2 provided the best accuracy for prediction of recurrence (76% accuracy, 71% sensitivity, 83% specificity, 90% positive predictive value, and 56% negative predictive value). Best accuracy for LAVI was ≥ 48 mL/m2 (70% accuracy, 53% sensitivity, 79% specificity, 85% positive predictive value; 43% negative predictive value). Conclusions RAVI is superior to LAVI for the prediction of AF recurrence at 6 months after DCCV.