Cryopreservation of a mother's oocytes for possible future use by her daughter with Turner syndrome: case report

• Published in: Fertility and sterility Vol. 90; no. 5; pp. 2008.e9 - 2008.e12
• Main Authors: Gidoni, Yariv S., M.D, Takefman, Janet, Ph.D, Holzer, Hananel E.G., M.D, Elizur, Shai E., M.D, Son, Weon-Young, Ph.D, Chian, Ri-Cheng, Ph.D, Tan, Seang Lin, M.D., M.B.A
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.11.2008
• Subjects: Adult; Child; Cryopreservation; Female; fertility preservation; Fertilization in Vitro; Humans; Infertility, Female - etiology; Infertility, Female - therapy; intergenerational gamete donation; Internal Medicine; Obstetrics and Gynecology; Oocyte Donation; Oocyte Retrieval; oocyte vitrification; Ovulation Induction; Tissue Preservation; Turner syndrome; Turner Syndrome - complications; fertility preservation; oocyte vitrification; Turner syndrome; intergenerational gamete donation
• ISSN: 0015-0282; 1556-5653
• DOI: 10.1016/j.fertnstert.2008.05.050

Objective To report a new fertility alternative for women with Turner syndrome, who are rendered infertile, by having their mothers freeze their own oocytes for the purpose of donating to their daughters when they are adults. Design Case report. Setting Academic teaching hospital. Patient(s) A 33-year-old healthy mother of three children; and her second child, a 6-year-old daughter recently diagnosed with Turner syndrome. Intervention(s) Mother-to-daughter oocyte donation combined with oocyte vitrification. Main Outcome Measure(s) Number of cryopreserved oocytes. Result(s) After three cycles of ovarian stimulation, 30 oocytes were cryopreserved for the daughter's possible future use. Conclusion(s) The treatment option presented here opens the door for the banking of a mother's oocytes as a possible donation to a young daughter with a medical condition that leads to infertility, for her possible future use.