PIXE study on the effects of parathyroid hormone on elemental content in rat bones

Highlights • A continuous hyper-secretion of parathyroid hormone leads to bone resorption. • The toxicity of high dose of PTH on BMC has been evaluated. • After the bone treatment of PTH, the bone mass seems to be enhanced. • The concentration of other elements has been increased excluding Zn....

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Published inPhysica medica Vol. 32; no. 12; pp. 1615 - 1620
Main Authors Eisa, M.H, Shen, H, Jin, W, Alaamer, Abdulaziz S, Al-Rajhi, M.A, Idriss, Hajo
Format Journal Article
LanguageEnglish
Published Italy Elsevier Ltd 01.12.2016
Subjects
Animals
Bone Density - drug effects
Dose-Response Relationship, Drug
Element content
Female
Femur - drug effects
Femur - metabolism
Femur - physiology
Male
Osteoporosis
Parathyroid hormone
Parathyroid Hormone - pharmacology
Particle induced X-ray emission
Radiology
Rat bone
Rats
Rats, Sprague-Dawley
Spectrometry, X-Ray Emission
Osteoporosis
Element content
Particle induced X-ray emission
Parathyroid hormone
Rat bone
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Summary:Highlights • A continuous hyper-secretion of parathyroid hormone leads to bone resorption. • The toxicity of high dose of PTH on BMC has been evaluated. • After the bone treatment of PTH, the bone mass seems to be enhanced. • The concentration of other elements has been increased excluding Zn.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1120-1797
1724-191X
DOI:10.1016/j.ejmp.2016.11.117