2014 Focused Update of the Canadian Cardiovascular Society Guidelines for the Management of Atrial Fibrillation

• Published in: Canadian journal of cardiology Vol. 30; no. 10; pp. 1114 - 1130
• Main Authors: Verma, Atul, MD, Cairns, John A., MD, Mitchell, L. Brent, MD, Macle, Laurent, MD, Stiell, Ian G., MD, Gladstone, David, MD, McMurtry, Michael Sean, MD, Connolly, Stuart, MD, Cox, Jafna L., MD, Dorian, Paul, MD, Ivers, Noah, MD, Leblanc, Kori, PharmD, Nattel, Stanley, MD, Healey, Jeff S., MD
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 01.10.2014
• Subjects: Algorithms; Anticoagulants - therapeutic use; Antithrombins - administration & dosage; Aspirin - administration & dosage; Atrial Fibrillation - epidemiology; Atrial Fibrillation - therapy; Benzimidazoles - administration & dosage; beta-Alanine - administration & dosage; beta-Alanine - analogs & derivatives; Canada; Cardiovascular; Comorbidity; Dabigatran; Electric Countershock; Humans; Renal Insufficiency, Chronic - epidemiology; Risk Assessment; Stroke - epidemiology; Stroke - prevention & control; Ticlopidine - administration & dosage; Ticlopidine - analogs & derivatives; Canada
• ISSN: 0828-282X; 1916-7075
• DOI: 10.1016/j.cjca.2014.08.001

Abstract Atrial fibrillation (AF) is an extremely common clinical problem with an important population morbidity and mortality burden. The management of AF is complex and fraught with many uncertain and contentious issues, which are being addressed by extensive ongoing basic and clinical research. The Canadian Cardiovascular Society AF Guidelines Committee produced an extensive set of evidence-based AF management guidelines in 2010 and updated them in the areas of anticoagulation and rate/rhythm control in 2012. In late 2013, the committee judged that sufficient new information regarding AF management had become available since 2012 to warrant an update to the Canadian Cardiovascular Society AF Guidelines. After extensive evaluation of the new evidence, the committee has updated the guidelines for: (1) stroke prevention principles; (2) anticoagulation of AF patients with chronic kidney disease; (3) detection of AF in patients with stroke; (4) investigation and management of subclinical AF; (5) left atrial appendage closure in stroke prevention; (6) emergency department management of AF; (7) periprocedural anticoagulation management; and (8) rate and rhythm control including catheter ablation. This report presents the details of the updated recommendations, along with their background and rationale. In addition, a complete set of presently applicable recommendations, those that have been updated and those that remain in force from previous guideline versions, is provided in the Supplementary Material.