Dangers of mRNA vaccines

• Published in: Industrial psychiatry journal Vol. 30; no. 3; pp. 291 - 293
• Main Authors: Ali, Tahoora, Mujawar, Swaleha, Sowmya, A, Saldanha, Daniel, Chaudhury, Suprakash
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer India Pvt. Ltd 01.10.2021; Medknow Publications and Media Pvt. Ltd; Medknow Publications & Media Pvt. Ltd; Wolters Kluwer - Medknow; Wolters Kluwer Medknow Publications
• Subjects: absolute risk reduction; biontech; Contemporary Issue; COVID-19; Messenger RNA; moderna; mrna vaccine; mRNA vaccines; pfizer; Pharmaceutical industry; reactogenicity; relative risk reduction; vaccine; vaccine hesitancy; Vaccines; United States; COVID-19; relative risk reduction; vaccine hesitancy; vaccine; moderna; BioNTech; Absolute risk reduction; reactogenicity; pfizer; mRNA vaccine
• ISSN: 0972-6748; 0976-2795
• DOI: 10.4103/0972-6748.328833

"Necessity is the mother of invention:" An adage was brought to life with the emergence of the mRNA vaccine against the backdrop of the foreboding and mercurial COVID-19 pandemic. Considering a negligible adverse-effect profile and a break-neck manufacturing speed, it shone bright as the ideal vaccine candidate. However, "all that glitters is not gold," as was evidenced by the significant reactogenicity, a host of multi-systemic side-effects, that are being reported by the vaccine recipients; which is palpably resulting in a shift of emotions for the vaccine, accounting for vaccine hesitancy. Anaphylaxis, antibody-dependent enhancements, and deaths, comprise the most serious side-effects, albeit occurring in sparing numbers. Storage and transportation require fastidious temperatures, rendering it substantially inaccessible to a country like India. The biggest jolt, however, was the unfolding of the biases in reporting vaccine efficacy, as only the attractively high numbers of the relatively equivocal relative risk reduction were reported while keeping at bay the meager numbers of the more forthright absolute risk reduction. Notwithstanding the fallacies, the mRNA vaccine still promises hope; and with the right precautions and finesse, can be potentiated, as "a watched pot never boils."