Familial Himalayan P Wave and Left Ventricular Hypertrabeculation/Noncompaction

• Published in: Annals of noninvasive electrocardiology Vol. 20; no. 2; pp. 181 - 186
• Main Authors: Stöllberger, Claudia, Avanzini, Marion, Siostrzonek, Peter, Kühn, Peter, Winkler, Walther‐Benedikt, Finsterer, Josef
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.03.2015; John Wiley and Sons Inc
• Subjects: Adult; Cardiomyopathy; Cardiomyopathy, Hypertrophic - complications; Cardiomyopathy, Hypertrophic - diagnosis; Cardiomyopathy, Hypertrophic - surgery; Case Report; Case Reports; Clinical outcomes; Electrocardiography - methods; Fatal Outcome; Female; Genetic Predisposition to Disease; giant P wave; Heart Defects, Congenital - complications; Heart Defects, Congenital - diagnosis; Heart Defects, Congenital - surgery; Heart Transplantation; Humans; hypertrophic cardiomyopathy; left ventricular noncompaction; Male; Medical equipment; Middle Aged; Pacemaker, Artificial; Ventricular Dysfunction, Left - complications; Ventricular Dysfunction, Left - diagnosis; Ventricular Dysfunction, Left - surgery; Young Adult; hypertrophic cardiomyopathy; giant P wave; cardiomyopathy; left ventricular noncompaction
• ISSN: 1082-720X; 1542-474X
• DOI: 10.1111/anec.12159

Background “Himalayan P waves,” are reported in congenital heart disease and cardiomyopathies. Methods We report a family with hypertrophic cardiomyopathy, Himalayan P waves, extensive focal right atrial wall thickening and left ventricular hypertrabeculation/noncompaction (LVHT). Results The father received a pacemaker and underwent heart transplantation because of hypertrophic cardiomyopathy. His daughters showed Himalayan P waves and right atrial wall thickening. LVHT was diagnosed in sister A at age 23 years and developed in sister B between 42 and 46 years. In sister A the heart rate continuously declined. She refused implantation of a pacemaker and died with 49 years. Sister B, suffers from bradycardia. Conclusions Himalayan P waves are due to focal right atrial wall thickening, may be familially and associated with LVHT.