Sleep induced by small doses of tubocurarine injected into cerebral ventricles of dog

Summary In unanaesthetized dogs, sleep with the typical sleep pattern in the E.E.G. was produced with (+)‐tubocurarine when injected in a small dose (500 ng) into, or perfused in low concentration (100 ng/ml) through the cerebral ventricles.

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Bibliographic Details
Published inBritish journal of pharmacology Vol. 49; no. 1; pp. 23 - 28
Main Authors HARANATH, P. S. R. K., SHYAMALAKUMARI, S.
Format Journal Article
LanguageEnglish
Published Oxford, UK Blackwell Publishing Ltd 01.09.1973
Subjects
Animals
Cerebral Ventricles
Dogs
Electroencephalography
Female
Injections
Male
Perfusion
Sleep - drug effects
Sleep, REM - drug effects
Systematic Pharmacology
Tubocurarine - pharmacology
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Summary:Summary In unanaesthetized dogs, sleep with the typical sleep pattern in the E.E.G. was produced with (+)‐tubocurarine when injected in a small dose (500 ng) into, or perfused in low concentration (100 ng/ml) through the cerebral ventricles.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0007-1188
1476-5381
DOI:10.1111/j.1476-5381.1973.tb08264.x