Bio-actuated microvalve in microfluidics using sensing and actuating function of Mimosa pudica

• Published in: Scientific reports Vol. 12; no. 1; p. 7653
• Main Authors: Aishan, Yusufu, Funano, Shun-Ichi, Sato, Asako, Ito, Yuri, Ota, Nobutoshi, Yalikun, Yaxiaer, Tanaka, Yo
• Format: Journal Article
• Language: English
• Published: England Nature Publishing Group 23.05.2022; Nature Publishing Group UK; Nature Portfolio
• Subjects: Blood vessels; Cardiomyocytes; Microelectromechanical systems; Microfluidics; Mimosa pudica; Power supply
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-022-11637-3

Bio-actuators and sensors are increasingly employed in microscale devices for numerous applications. Unlike other artificial devices actuated by living cells or tissues, here we introduce a microvalve system actuated by the stimuli-responsive action plant, Mimosa pudica (sleepy plant). This system realizes the control of the valve to open and close by dropping and recovering responses of Mimosa pudica branch upon external physical stimulations. The results showed that one matured single uncut Mimosa pudica branch produced average force of 15.82 ± 0.7 mN. This force was sufficient for actuating and keeping the valve open for 8.46 ± 1.33 min in a stimulation-recovering cycle of 30 min. Additionally, two separately cut Mimosa pudica branches were able to keep the valve open for 2.28 ± 0.63 min in a stimulating-recovering cycle of 20min. The pressure resistance and the response time of the valve were 4.2 kPa and 1.4 s, respectively. This demonstration of plant-microfluidics integration encourages exploiting more applications of microfluidic platforms that involve plant science and plant energy harvesting.