Hepatocyte hopping of OATP1B substrates contributes to efficient hepatic detoxification

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Bibliographic Details
Published inClinical pharmacology and therapeutics Vol. 92; no. 5; p. 559
Main Authors Iusuf, D, van de Steeg, E, Schinkel, A H
Format Journal Article
LanguageEnglish
Published United States 01.11.2012
Subjects
Animals
Anions
Biological Transport
Cations
Drug-Related Side Effects and Adverse Reactions
Hepatocytes - metabolism
Humans
Hydrophobic and Hydrophilic Interactions
Liver - metabolism
Liver - pathology
Organic Anion Transporters - metabolism
Organic Anion Transporters, Sodium-Independent - metabolism
Pharmaceutical Preparations - chemistry
Pharmaceutical Preparations - metabolism
Solute Carrier Organic Anion Transporter Family Member 1b1
Solute Carrier Organic Anion Transporter Family Member 1B3
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ISSN:1532-6535
DOI:10.1038/clpt.2012.143