Palladium‐Loaded Cucurbit[7]uril‐Modified Iron Oxide Nanoparticles for C−C Cross‐Coupling Reactions

• Published in: Chemistry : a European journal Vol. 24; no. 10; pp. 2349 - 2353
• Main Authors: Benyettou, Farah, Motte, Laurence, Traboulsi, Hassan, Mazher, Javed, Pasricha, Renu, Olsen, John‐Carl, Trabolsi, Ali, Guenin, Erwan
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 16.02.2018; Wiley-VCH Verlag
• Subjects: Aerobic conditions; Catalysis; Catalysts; Chemical and Process Engineering; Chemical reactions; Chemistry; Coupling; Cross coupling; cross-coupling reactions; cucurbituril; Engineering Sciences; Environmental Engineering; Environmental Sciences; Ethanol; Iron oxides; macrocyclic chemistry; magnetic nano-catalyst; Nanoparticles; Palladium; palladium; magnetic nano-catalyst; cucurbituril; cross-coupling reactions; macrocyclic chemistry
• ISSN: 0947-6539; 1521-3765
• DOI: 10.1002/chem.201705082

Cucurbit[7]uril modified iron oxide nanoparticles (CB[7]NPs) were loaded with palladium to form nano‐catalysts (Pd@CB[7]NPs) that, with microwave heating, catalysed Suzuki–Miyaura, Sonogashira, and Mizoroki–Heck cross‐coupling reactions. Reactions were run in environmentally benign 1:1 ethanol/water solvent under convenient aerobic conditions. In a preliminary screening, conversions and yields were uniformly high with turn over frequencies (TOF) ranging from 64 to 7360 h−1. The nano‐catalysts could be recovered with a magnet and reused several times (6 times for Suzuki–Miayura reaction) without loss of activity. Cucurbit[7]uril modified iron‐oxide nanoparticles (CB[7]NPs) were loaded with palladium to form nano‐catalysts (Pd@CB[7]NPs) that, with microwave heating, catalysed Suzuki–Miyaura, Sonogashira, and Mizoroki–Heck cross‐coupling reactions.