Catheter-related bloodstream Mycobacterium wolinskyi infection in an umbilical cord blood transplant recipient: a case report

Catheter-related bloodstream infection (CRBSI), caused by rapidly growing mycobacteria (RGM), is a rare infectious complication in hematopoietic stem cell transplant (HSCT) recipients and can often be misdiagnosed as Gram-positive rod (GPR) bacteremia. We present a case of CRBSI caused by Mycobacter...

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Bibliographic Details
Published inBMC infectious diseases Vol. 22; no. 1; p. 520
Main Authors Muranaka, Emiri, Hase, Ryota, Utsu, Yoshikazu, Watari, Tomohisa, Otsuka, Yoshihito, Hosokawa, Naoto
Format Journal Article
LanguageEnglish
Published England BioMed Central Ltd 04.06.2022
BioMed Central
BMC
Subjects
Acids
Bacteremia
Blood
Blood culture
Case Report
Case reports
Case studies
Catheters
Causes of
Cell culture
Complications and side effects
Cord blood
Culture media
Endocarditis
Fetal blood
Hematopoietic stem cells
Immunocompromised hosts
Infections
Infectious diseases
Intravenous catheterization
Laboratories
Leukemia
Medical instruments
Mycobacterial infections
Mycobacterium
Mycobacterium wolinskyi
Nosocomial infections
Patients
Prostheses
Rapidly growing mycobacteria
Stem cell transplantation
Stem cells
Transplantation
Umbilical cord
Umbilical cord blood transplant
Unidentifiable Gram-positive rods
Japan
Unidentifiable Gram-positive rods
Case report
Mycobacterium wolinskyi
Rapidly growing mycobacteria
Umbilical cord blood transplant
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Summary:Catheter-related bloodstream infection (CRBSI), caused by rapidly growing mycobacteria (RGM), is a rare infectious complication in hematopoietic stem cell transplant (HSCT) recipients and can often be misdiagnosed as Gram-positive rod (GPR) bacteremia. We present a case of CRBSI caused by Mycobacterium wolinskyi, a rare RGM, in a 44-year-old female patient who received an umbilical cord blood transplant. Rapidly growing mycobacteria can stain as GPRs and may grow in routine blood culture media after 3-4 days of incubation. These features are not widely known to clinicians, and acid-fast staining is therefore recommended when unidentifiable GPRs are detected in blood cultures, especially in immunocompromised patients, such as those with hematologic malignancies or intravascular devices.
Bibliography:ObjectType-Case Study-2
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ISSN:1471-2334
1471-2334
DOI:10.1186/s12879-022-07495-z