A mind-brain-body dataset of MRI, EEG, cognition, emotion, and peripheral physiology in young and old adults

We present a publicly available dataset of 227 healthy participants comprising a young (N=153, 25.1±3.1 years, range 20-35 years, 45 female) and an elderly group (N=74, 67.6±4.7 years, range 59-77 years, 37 female) acquired cross-sectionally in Leipzig, Germany, between 2013 and 2015 to study mind-b...

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Published inScientific data Vol. 6; no. 1; p. 180308
Main Authors Babayan, Anahit, Erbey, Miray, Kumral, Deniz, Reinelt, Janis D, Reiter, Andrea M F, Röbbig, Josefin, Schaare, H Lina, Uhlig, Marie, Anwander, Alfred, Bazin, Pierre-Louis, Horstmann, Annette, Lampe, Leonie, Nikulin, Vadim V, Okon-Singer, Hadas, Preusser, Sven, Pampel, André, Rohr, Christiane S, Sacher, Julia, Thöne-Otto, Angelika, Trapp, Sabrina, Nierhaus, Till, Altmann, Denise, Arelin, Katrin, Blöchl, Maria, Bongartz, Edith, Breig, Patric, Cesnaite, Elena, Chen, Sufang, Cozatl, Roberto, Czerwonatis, Saskia, Dambrauskaite, Gabriele, Dreyer, Maria, Enders, Jessica, Engelhardt, Melina, Fischer, Marie Michele, Forschack, Norman, Golchert, Johannes, Golz, Laura, Guran, C Alexandrina, Hedrich, Susanna, Hentschel, Nicole, Hoffmann, Daria I, Huntenburg, Julia M, Jost, Rebecca, Kosatschek, Anna, Kunzendorf, Stella, Lammers, Hannah, Lauckner, Mark E, Mahjoory, Keyvan, Kanaan, Ahmad S, Mendes, Natacha, Menger, Ramona, Morino, Enzo, Näthe, Karina, Neubauer, Jennifer, Noyan, Handan, Oligschläger, Sabine, Panczyszyn-Trzewik, Patricia, Poehlchen, Dorothee, Putzke, Nadine, Roski, Sabrina, Schaller, Marie-Catherine, Schieferbein, Anja, Schlaak, Benito, Schmidt, Robert, Gorgolewski, Krzysztof J, Schmidt, Hanna Maria, Schrimpf, Anne, Stasch, Sylvia, Voss, Maria, Wiedemann, Annett, Margulies, Daniel S, Gaebler, Michael, Villringer, Arno
Format Journal Article
LanguageEnglish
Published England Nature Publishing Group 12.02.2019
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Summary:We present a publicly available dataset of 227 healthy participants comprising a young (N=153, 25.1±3.1 years, range 20-35 years, 45 female) and an elderly group (N=74, 67.6±4.7 years, range 59-77 years, 37 female) acquired cross-sectionally in Leipzig, Germany, between 2013 and 2015 to study mind-body-emotion interactions. During a two-day assessment, participants completed MRI at 3 Tesla (resting-state fMRI, quantitative T1 (MP2RAGE), T2-weighted, FLAIR, SWI/QSM, DWI) and a 62-channel EEG experiment at rest. During task-free resting-state fMRI, cardiovascular measures (blood pressure, heart rate, pulse, respiration) were continuously acquired. Anthropometrics, blood samples, and urine drug tests were obtained. Psychiatric symptoms were identified with Standardized Clinical Interview for DSM IV (SCID-I), Hamilton Depression Scale, and Borderline Symptoms List. Psychological assessment comprised 6 cognitive tests as well as 21 questionnaires related to emotional behavior, personality traits and tendencies, eating behavior, and addictive behavior. We provide information on study design, methods, and details of the data. This dataset is part of the larger MPI Leipzig Mind-Brain-Body database.
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PMCID: PMC6371893
Conception, design, and preparation of the manuscript (Core LEMON group): Anahit Babayan, Miray Erbey, Andrea M.F. Reiter, Josefin Röbbig, H. Lina Schaare, Deniz Kumral, Janis D. Reinelt, Marie Uhlig, Michael Gaebler, Arno Villringer. Contribution to study design: Alfred Anwander, Pierre-Louis Bazin, Annette Horstmann, Leonie Lampe, Daniel S. Margulies, Hadas Okon-Singer, André Pampel, Christiane S. Rohr, Julia Sacher, Angelika Thöne-Otto, Sabrina Trapp, Roberto Cozatl, Karina Näthe, Sven Preusser, Anne Schrimpf, Norman Forschack, Till Nierhaus, Krzysztof J. Gorgolewski. Quality control of MRI data: Miray Erbey, Andrea M. F. Reiter, Josefin Röbbig, H. Lina Schaare, Deniz Kumral, Janis D. Reinelt, Marie Uhlig, Michael Gaebler. MRI data preprocessing: Julia M. Huntenburg, Deniz Kumral, H. Lina Schaare, Ahmad S. Kaanan. EEG data quality control and preprocessing: Keyvan Mahjoory, Elena Cesnaite, Vadim V. Nikulin. Behavioral data analyses: Josefin Röbbig, Maria Blöchl. Medical Briefing: Katrin Arelin, Janis D. Reinelt, Anna Kosatschek. Recruiting participants and data acquisition (Core LEMON group, and medical or student assistants): Anahit Babayan, Miray Erbey, Andrea M. F. Reiter, Josefin Röbbig, H. Lina Schaare, Deniz Kumral, Janis D. Reinelt, Marie Uhlig, Michael Gaebler, Denise Altmann, Edith Bongartz, Patric Breig, Sufang Chen, Saskia Czerwonatis, Gabriele Dambrauskaite, Maria Dreyer, Jesica Enders, Melina Engelhardt, Marie Michele Fischer, Johannes Golchert, Laura Golz, C. Alexandrina Guran, Susanna Hedrich, Nicole Hentschel, Daria I. Hoffmann, Rebecca Jost, Stella Kunzendorf, Hannah Lammers, Mark E. Lauckner, Natacha Mendes, Ramona Menger, Enzo Morino, Jennifer Neubauer, Handan Noyan, Sabine Oligschläger, Patricia Panczyszyn-Trzewik, Dorothee Poehlchen, Nadine Putzke, Sabrina Roski, Marie-Catherine Schaller, Anja Schieferbein, Benito Schlaak, Hanna Maria Schmidt, Robert Schmidt, Sylvia Stasch, Maria Voss, Anett Wiedemann. All authors critically reviewed and approved the final version of the manuscript.
ISSN:2052-4463
2052-4463
DOI:10.1038/sdata.2018.308