Dietary Lactobacillus reuteri SL001 Improves Growth Performance, Health-Related Parameters, Intestinal Morphology and Microbiota of Broiler Chickens

• Published in: Animals (Basel) Vol. 13; no. 10; p. 1690
• Main Authors: Chai, Chunli, Guo, Yaowen, Mohamed, Taha, Bumbie, Gifty Z, Wang, Yan, Zeng, Xiaojing, Zhao, Jinghua, Du, Huamao, Tang, Zhiru, Xu, Yetong, Sun, Weizhong
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 19.05.2023; MDPI
• Subjects: Abundance; Alzheimer's disease; Animal models; Animals; Antibiotics; Antioxidants; Bacitracin; Bacteria; broiler; Cecum; Chickens; Cholesterol; Creatinine; Crypts; Cytokines; Diet; Drug resistance; Feeds; Gene expression; Globulins; growth performance; gut microbiota; Humidity; Ileum; Immunoglobulins; Immunology; Interleukin 4; Interleukin 6; intestinal morphology; Intestine; Jejunum; Lactobacillus reuteri; Lactobacillus reuteri SL001; Lipoproteins; Lipoproteins (very low density); Low density lipoprotein; Microbiota; Microorganisms; Morphology; Parameters; Poultry; Probiotics; Rabbits; Relative abundance; serum biochemistry; Small intestine; Triglycerides; Tumor necrosis factor-TNF; Uric acid; Zinc bacitracin; United States > US; China; serum biochemistry; growth performance; Lactobacillus reuteri SL001; intestinal morphology; gut microbiota; broiler
• ISSN: 2076-2615; 2076-2615
• DOI: 10.3390/ani13101690

It was assumed that dietary inclusion of SL001 isolated from the gastric contents of rabbits could act as an alternative to feed antibiotics to improve the growth performance of broiler chickens. We randomly assigned 360 one-day-old AA white-feathered chicks in three treatments: basal diet (control), basal diet plus zinc bacitracin (antibiotic), and basal diet plus SL001 (SL001) treatment. The results showed the total BW gain and average daily gain (ADG) of broilers in SL001 treatment increased significantly ( < 0.05, respectively) compared with the control group from day 0 to 42. Moreover, we observed higher levels of immune globulins in both the SL001 group and the antibiotic group. Total antioxidant capacity and levels of antioxidant factors were also significantly increased ( ≤ 0.05, respectively) in the SL001 treatment group, while the interleukin 6, interleukin 4, creatinine, uric acid, total cholesterol, triglyceride, VLDL, LDL and malondialdehyde were remarkably decreased ( < 0.05, respectively). In the ileum of SL001 treatment broilers, the height of villi and the ratio of villi height to crypt depth were significantly increased ( < 0.05). Meanwhile, the crypt depth reduced ( < 0.01) and the ratio of villi height to crypt depth increased ( < 0.05) in the jejunum compared to the control. The abundance of microbiota increased in the gut of broilers supplemented with SL001. Dietary SL001 significantly increased the relative abundance of Actinobacteria in the cecal contents of broilers ( < 0.01) at the phylum level. In conclusion, SL001 supplementation promotes the growth performance of broiler chickens and exhibits the potential application value in the industry of broiler feeding.