A hemodialysis patient with Mycobacterium avium complex pericarditis in which remarkable presepsin elevation was not accompanied by procalcitonin elevation

Abstract Background The application of presepsin for diagnosing infections in hemodialysis (HD) patients has not been confirmed yet. In addition, whether presepsin can detect atypical mycobacterial infection or not remains unknown. Case presentation We describe the case of a 66-year-old male HD pati...

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Bibliographic Details
Published inRenal replacement therapy Vol. 6; no. 1; pp. 20 - 4
Main Author Shiota, Jun
Format Journal Article
LanguageEnglish
Published London Springer Nature B.V 16.04.2020
BMC
Subjects
Antibiotics
Antibodies
Antigens
Biomarkers
Blood
Case reports
Cytokines
Cytomegalovirus
Epstein-Barr virus
Granulomas
Hemodialysis
HIV
Human immunodeficiency virus
Immunocompetence
Infections
Kidney diseases
Laboratories
Mycobacterium avium complex
Patients
Pericarditis
Plasma
Presepsin
Procalcitonin
Japan
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Summary:Abstract Background The application of presepsin for diagnosing infections in hemodialysis (HD) patients has not been confirmed yet. In addition, whether presepsin can detect atypical mycobacterial infection or not remains unknown. Case presentation We describe the case of a 66-year-old male HD patient with pericardial tamponade. Mycobacterium avium complex (MAC) was identified from a culture of pericardial effusion. The patient showed a clinical improvement after approximately 1 year without the administration of antibiotics. Remarkably, high plasma presepsin values were observed without an increase in serum procalcitonin values. The patient’s presepsin values decreased after the treatment of MAC induced pericarditis. Conclusions We found a HD patient with mycobacterium avium complex pericarditis with remarkable presepsin elevation unaccompanied by PCT elevation.
ISSN:2059-1381
2059-1381
DOI:10.1186/s41100-020-00269-w