Imaging Nano–Bio Interactions in the Kidney: Toward a Better Understanding of Nanoparticle Clearance

All clear! Highlighted is work aimed at a better understanding of nano–bio interactions for rational design of renal‐clearable nanoparticles in diseased kidneys. Renal clearance of ultra‐small gold nanoparticles (AuNPs) is not only dependent upon the Choi criteria but is also affected by the microph...

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Bibliographic Details
Published inAngewandte Chemie International Edition Vol. 57; no. 12; pp. 3008 - 3010
Main Authors Wang, Junqing, Liu, Gang
Format Journal Article
LanguageEnglish
Published Germany Wiley Subscription Services, Inc 12.03.2018
EditionInternational ed. in English
Subjects
Gold
Gold - chemistry
Gold - pharmacokinetics
Humans
imaging agents
kidney
Kidney - chemistry
Kidney - metabolism
Kidneys
Metal Nanoparticles - chemistry
Nanomedicine
Nanoparticles
Particle Size
Surface Properties
gold
kidney
nanomedicine
nanoparticles
imaging agents
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Summary:All clear! Highlighted is work aimed at a better understanding of nano–bio interactions for rational design of renal‐clearable nanoparticles in diseased kidneys. Renal clearance of ultra‐small gold nanoparticles (AuNPs) is not only dependent upon the Choi criteria but is also affected by the microphysiological structure of the glomerular barrier and the pathophysiological changes in the nephron.
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ISSN:1433-7851
1521-3773
1521-3773
DOI:10.1002/anie.201711705