CT-resolution regional hyperthermia treatment planning
Recent development of quasistatic zooming has enabled the computation of mm-resolution SAR distributions within reasonable computation times. These high-resolution SAR distributions proved to be completely dissimilar from the cm-resolution distributions. To study the impact of high-resolution SAR mo...
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Published in | International journal of hyperthermia Vol. 18; no. 2; pp. 104 - 116 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
London
Informa UK Ltd
2002
Taylor & Francis |
Subjects | |
Online Access | Get full text |
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Summary: | Recent development of quasistatic zooming has enabled the computation of mm-resolution SAR distributions within reasonable computation times. These high-resolution SAR distributions proved to be completely dissimilar from the cm-resolution distributions. To study the impact of high-resolution SAR modelling on regional hyperthermia treatment planning (HTP), a conventional, low-resolution treatment plan is compared to an high-resolution plan. This comparison shows that the high-resolution plan yields totally different SAR and temperature distributions when compared to the conventional plan. Both SAR and temperature maxima predicted by the low-resolution plan are not predicted by the high-resolution plan and, even worse, the low-resolution plan fails to predict maxima that are predicted by the high-resolution plan. Furthermore, it appears that small-scale SAR maxima can result in temperature maxima which may cause treatment-limiting hot spots. These small-scale SAR maxima appear to be highly determined by the dielectric geometry of the patient. This demonstrates the need for an accurate, high-resolution description of this dielectric geometry. Moreover, it suggests that it may be very difficult to reduce potential treatment-limiting hot spots in clinical practice. This study demonstrates the need for high-resolution regional hyperthermia treatment planning. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0265-6736 1464-5157 |
DOI: | 10.1080/02656730110092620 |