Eating disorders and emotional dysregulation are associated with insufficient weight loss after bariatric surgery: a 1-year observational follow-up study

• Published in: Eating and weight disorders Vol. 28; no. 1; p. 49
• Main Authors: Barbuti, Margherita, Carignani, Giulia, Weiss, Francesco, Calderone, Alba, Fierabracci, Paola, Salvetti, Guido, Menculini, Giulia, Tortorella, Alfonso, Santini, Ferruccio, Perugi, Giulio
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 02.06.2023; Springer Nature B.V
• Subjects: Adult; Attention deficit hyperactivity disorder; Bariatric Surgery - psychology; Body mass index; Eating disorders; Emotional regulation; Feeding and Eating Disorders - complications; Follow-Up Studies; Gastrointestinal surgery; Humans; Medicine; Medicine & Public Health; Mental disorders; Obesity; Psychiatry; Psychopathology; Surgical outcomes; Weight control; Weight Loss - physiology; Mood disorders; Emotional dysregulation; Obesity; Binge eating disorder; Bariatric surgery; Weight loss
• ISSN: 1590-1262; 1124-4909; 1590-1262
• DOI: 10.1007/s40519-023-01574-z

Purpose Subjects with obesity, especially those seeking bariatric surgery, exhibit high rates of mental disorders and marked psychopathological traits. The primary objective of this prospective, non-interventional study was to investigate whether the presence of different psychiatric disorders, attention deficit/hyperactivity disorder (ADHD) symptomatology and emotional dysregulation influenced weight loss at 1-year follow-up after surgery. Methods Subjects consecutively referred for pre-surgical evaluation at the Obesity Center of Pisa University Hospital were recruited. Psychiatric diagnoses were made through the Mini-International Neuropsychiatric Interview (MINI) and ADHD symptomatology was assessed with the Wender–Reimherr Adult Attention Deficit Disorder Scale (WRAADDS). Emotional dysregulation was investigated through the WRAADDS and self-report questionnaires. After surgery, weight and obesity-related comorbidities were monitored during follow-up. Results Of the 99 participants recruited, 76 underwent surgery and 65 could be reevaluated 1 year after surgery. Subjects with insufficient weight loss (excess body mass index loss ≤ 53%, n  = 15) had more frequent lifetime binge eating disorder (BED) and BED-mood disorders comorbidity than subjects with favorable post-surgical outcome. Additionally, they scored higher on both physician-administered and self-report scales assessing emotional dysregulation, which represents a nuclear symptom of ADHD in adults. At the logistic regression analysis, older age, higher preoperative excess body mass index and greater affective instability were predictors of reduced weight loss at 1-year follow-up. Conclusion Emotional dysregulation seems to be associated with a worse outcome after bariatric surgery. Further studies with larger samples and longer follow-up are needed to confirm the influence of different psychiatric disorders and psychopathological traits on post-surgical outcome. Level of evidence V, prospective descriptive study.