Fatal sepsis by Klebsiella pneumoniae in a patient with systemic lupus erythematosus: the importance of postmortem microbiological examination for the ex post diagnosis of infection

The utility of postmortem microbiology has continuously been a topic of controversy. The present study describes a case of fatal sepsis in a patient with systemic lupus erythematosus. Postmortem culture and genotyping analyses allowed us to identify Klebsiella pneumoniae as the cause of sepsis, reve...

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Published inInternational Journal of Legal Medicine Vol. 129; no. 5; pp. 1097 - 1101
Main Authors D’Ovidio, Cristian, Pompilio, Arianna, Crocetta, Valentina, Gherardi, Giovanni, Carnevale, Aldo, Di Bonaventura, Giovanni
Format Journal Article Book Review
LanguageEnglish
Published Berlin/Heidelberg Springer Berlin Heidelberg 01.09.2015
Springer Nature B.V
Subjects
Adult
Case Report
Fatal Outcome
Forensic Medicine
Genotype
Humans
Klebsiella Infections - complications
Klebsiella Infections - diagnosis
Klebsiella pneumoniae
Klebsiella pneumoniae - genetics
Klebsiella pneumoniae - isolation & purification
Lupus Erythematosus, Systemic - complications
Male
Medical Law
Medicine
Medicine & Public Health
Sepsis - microbiology
Sepsis
Postmortem microbiology
Systemic lupus erythematosus
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Summary:The utility of postmortem microbiology has continuously been a topic of controversy. The present study describes a case of fatal sepsis in a patient with systemic lupus erythematosus. Postmortem culture and genotyping analyses allowed us to identify Klebsiella pneumoniae as the cause of sepsis, revealing the inadequateness of antimicrobial therapy.
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ISSN:0937-9827
1437-1596
DOI:10.1007/s00414-015-1160-z