Biogenic Zinc Oxide Nanoparticles and Their Biomedical Applications: A Review

• Published in: Journal of inorganic and organometallic polymers and materials Vol. 33; no. 6; pp. 1437 - 1452
• Main Authors: Jha, Shruti, Rani, Ritu, Singh, Sandeep
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.06.2023; Springer Nature B.V
• Subjects: Biocompatibility; Biomedical materials; Chemistry; Chemistry and Materials Science; COVID-19; Inorganic Chemistry; Medical electronics; Metal oxides; Nanomaterials; Nanoparticles; Nanotechnology; Organic Chemistry; Polymer Sciences; Reagents; Review; Severe acute respiratory syndrome coronavirus 2; Toxicity; Viral diseases; Viruses; Zinc oxide; Zinc oxides; ZnO NPs; SARS-CoV-2; Biogenic synthesis; Bio-medical applications; Nanotechnology
• ISSN: 1574-1443; 1574-1451
• DOI: 10.1007/s10904-023-02550-x

Nanotechnology has inscribed novel perception into the material science and one of the most extensively used nanomaterials is Zinc oxide nanoparticles (ZnO NPs) with healthcare and biomedical applications. Because of its outstanding biocompatibility, low toxicity, and low cost, ZnO NPs have become one of the most prominent metal oxide NPs in biological applications. This review highlights the different aspects of ZnO NPs, like their green synthesis as a substitute of conventional route due to avoidance of threat of hazardous, costly precursors and subsequent mostly therapeutic applications. Due to their wide bandwidth and high excitation binding energy, ZnO NPs have undergone extensive research. In addition to their potential applications as antibiotics, antioxidants, anti-diabetics, and cytotoxic agents, ZnO NPs also hold a promising future as an antiviral treatment for SARS-CoV-2. Zn has antiviral properties and may be effective against a variety of respiratory virus species, particularly SARS-CoV-2. This review includes a variety of topics, including the virus’s structural properties, an overview of infection mechanism, and current COVID-19 treatments. Nanotechnology-based techniques for the prevention, diagnosis, and treatment of COVID-19 are also discussed in this review.