A metabonomic investigation on the biochemical perturbation in post-stroke patients with depressive disorder (PSD)

• Published in: Metabolic brain disease Vol. 31; no. 2; pp. 279 - 287
• Main Authors: Ding, Xinghua, Liu, Ruoxu, Li, Wenkai, Ni, Hengjia, Liu, Yong, Wu, Dandan, Yang, Shuguang, Liu, Jing, Xiao, Bo, Liu, Shaojun
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.04.2016; Springer Nature B.V
• Subjects: Adult; Aged; Biochemistry; Biomedical and Life Sciences; Biomedicine; Depression - blood; Depressive Disorder - complications; Depressive Disorder - etiology; Female; Humans; Male; Metabolic Diseases; Metabolomics - methods; Middle Aged; Neurology; Neurosciences; Oncology; Original Article; Stroke - blood; Stroke - complications; Stroke Rehabilitation; Stroke rehabilitation; Metabonomics; GC/MS; Post-stroke depression
• ISSN: 0885-7490; 1573-7365
• DOI: 10.1007/s11011-015-9748-z

A metabonomics study based on GC/MS and multivariate statistical analysis was performed involving 28 post stroke depressed (PSD) patients, 27 post-stroke non-depressed (PSND) patients and 33 healthy subjects to investigate the biochemical perturbation in their plasma samples. The outcome of this stu...