Bioengineered silk scaffolds in 3D tissue modeling with focus on mammary tissues

• Published in: Materials Science & Engineering C Vol. 59; pp. 1168 - 1180
• Main Authors: Maghdouri-White, Yas, Bowlin, Gary L., Lemmon, Christopher A., Dréau, Didier
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.02.2016
• Subjects: Animals; Biocompatible Materials; Biomaterials; Biomedical materials; Bombyx; Breast tissue modeling; Electrospinning; Fibroins; Imaging, Three-Dimensional; In vitro testing; Molecular structure; Nanofibers; Scaffolds; Silk fibroin; Surgical implants; Three dimensional; Three dimensional models; Three-dimensional modeling; Tissue Engineering; Tissue Scaffolds; Breast tissue modeling; Silk fibroin; Tissue engineering; Electrospinning; Nanofibers; Scaffolds; Three-dimensional modeling

In vitro generation of three-dimensional (3D) biological tissues and organ-like structures is a promising strategy to study and closely model complex aspects of the molecular, cellular, and physiological interactions of tissue. In particular, in vitro 3D tissue modeling holds promises to further our...