Redefining precision radiotherapy through liquid biopsy

Precision radiotherapy refers to the ability to deliver radiation doses with sub-millimetre accuracy. It does not however consider individual variation in tumour or normal tissue response, failing to maximise tumour control and minimise toxicity. Combining precise delivery with personalised dosing,...

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Bibliographic Details
Published inBritish journal of cancer Vol. 129; no. 6; pp. 900 - 903
Main Authors McLaren, D. B., Aitman, T. J.
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 05.10.2023
Nature Publishing Group
Subjects
692/4028/67/1857
692/4028/67/69
Biomedical and Life Sciences
Biomedicine
Biopsy
Cancer Research
Cell-Free Nucleic Acids
Drug Resistance
Epidemiology
Humans
Liquid Biopsy
Molecular Medicine
Oncology
Perspective
Radiation Oncology
Radiation therapy
Targeted cancer therapy
Toxicity
Tumors
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Summary:Precision radiotherapy refers to the ability to deliver radiation doses with sub-millimetre accuracy. It does not however consider individual variation in tumour or normal tissue response, failing to maximise tumour control and minimise toxicity. Combining precise delivery with personalised dosing, through analysis of cell-free DNA, would redefine precision in radiotherapy.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0007-0920
1532-1827
DOI:10.1038/s41416-023-02398-5