Effects of Coenzyme Q10 Supplementation on Anthropometric Indices in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Obesity is related to increase in the incidence of morbidity and mortality. Previous studies have led to conflicting results regarding the effect of coenzyme Q10 (CoQ10) supplementation on anthropometric indices. This study aimed to evaluate the efficacy of CoQ10 supplementation on body weight, body...

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Published inInternational journal of preventive medicine Vol. 11; no. 1; p. 181
Main Authors Ghavami, Abed, Mohammadi, Hamed, Hadi, Amir, Ziaei, Rahele, Nattagh-Eshtivani, Elyas, Sheykhrobat, Mohammad Veysi, Askari, Gholamreza
Format Journal Article
LanguageEnglish
Published Iran Medknow Publications and Media Pvt. Ltd 01.01.2020
Medknow Publications & Media Pvt. Ltd
Wolters Kluwer - Medknow
Wolters Kluwer Medknow Publications
Subjects
Adults
Analysis
Body mass index
Body measurements
Body weight
Clinical trials
coq10
Enzymes
Health aspects
Meta-analysis
Review
Systematic review
Type 2 diabetes
ubiquinone
waist circumference
body weight
ubiquinone
meta-analysis
Body mass index
waist circumference
CoQ10
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Summary:Obesity is related to increase in the incidence of morbidity and mortality. Previous studies have led to conflicting results regarding the effect of coenzyme Q10 (CoQ10) supplementation on anthropometric indices. This study aimed to evaluate the efficacy of CoQ10 supplementation on body weight, body mass index (BMI), and waist circumference (WC) through a systematic review and meta-analysis of randomized controlled trials (RCTs). PubMed, Scopus, Web of Science, and Cochrane Library as well as the reference lists of the identified relevant RCTs were searched up to March 2019, and weighted mean differences (WMDs) were pooled by using the random-effects model. Twenty RCTs (976 participants) were eligible to be included in the systematic review. The meta-analysis revealed that CoQ10 supplementation had no effect on body weight (WMD = -0.04 kg; 95% confidence interval [CI]: -1.96, 1.6; = 0.0%), BMI (WMD = -0.06 kg/m ; 95% CI: -0.54, 0.42; = 0.0%), and WC (WMD = 0.79 cm; 95% CI: -2.83, 0.04; = 0.0%). CoQ10 supplementation might not improve anthropometric indices. Future well-designed trials are still needed to confirm these results.
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ISSN:2008-7802
2008-8213
DOI:10.4103/ijpvm.IJPVM_179_19