Review of Testicular Tumor: Diagnostic Approach and Management Outcome in Africa

• Published in: Research and reports in urology Vol. 12; pp. 35 - 42
• Main Authors: Cassell, Ayun, Jalloh, Mohamed, Ndoye, Medina, Yunusa, Bashir, Mbodji, Mouhamadou, Diallo, Abdourahmane, Gaye, Omar, Labou, Issa, Niang, Lamine, Gueye, Serigne
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis Ltd 01.01.2020; Dove; Dove Medical Press
• Subjects: Age; Biomarkers; Cancer; Chemotherapy; Cisplatin; Dehydrogenases; Family medical history; germ cell; Literature reviews; Low income groups; Lymphatic system; Males; Malignancy; Medical prognosis; Metastasis; Mortality; orchidectomy; Patients; Radiation therapy; Review; Risk factors; Studies; Testes; Testicular cancer; Tumors; Ultrasonic imaging; Nigeria; Mali; Senegal; Africa; testicular cancer; germ cell; orchidectomy
• ISSN: 2253-2447; 2253-2447
• DOI: 10.2147/RRU.S242398

Testicular cancer is a common malignancy in young males with higher incidence in developed nations but with the lowest incidence in Africa (0.3-0.6/100 000). Ironically, the global testicular cancer mortality rate has shown a reverse trend to its incidence with higher rates in low- and middle-income countries (0.5 per 100 000) than in high-income countries. Data from GLOBOCAN 2008 have shown relatively high mortality rates in sub-Saharan countries like Mali, Ethiopia, Niger and Malawi. The prognosis of testicular tumor is good with remarkable chemosensitivity to cisplatin-based regimen. Early diagnosis, careful staging and a multidisciplinary management approach is crucial to achieve this optimal result. These results are achievable in the sub-Saharan region if the relevant resources are appropriated for cancer care and clinical guidelines are formulated in a regional context.