Sinonasal Mucormycosis: A to Z

Mucormycosis caused by one of the members of Mucoraceae family, is one of the most rapidly spreading and fatal fungal infection occurring mostly in Diabetic or Immunocompromised patients especially in developing countries. 26 patients suffering from sinonasal mucormycosis admitted in SGRRIM&HS,...

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Published inIndian journal of otolaryngology, and head, and neck surgery Vol. 71; no. Suppl 3; pp. 1962 - 1971
Main Authors Singh, V. P., Bansal, Chetan, Kaintura, Madhuri
Format Journal Article
LanguageEnglish
Published New Delhi Springer India 01.11.2019
Springer Nature B.V
Subjects
Fungal infections
Head and Neck Surgery
Medicine
Medicine & Public Health
Original
Original Article
Otolaryngology
Otorhinolaryngology
Sinuses
Amphotericin
Invasive fungal sinusitis
Rhinocerebral mucormycosis
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Summary:Mucormycosis caused by one of the members of Mucoraceae family, is one of the most rapidly spreading and fatal fungal infection occurring mostly in Diabetic or Immunocompromised patients especially in developing countries. 26 patients suffering from sinonasal mucormycosis admitted in SGRRIM&HS, Dehradun from January 2013 to January 2017 are discussed. Diagnosis of mucormycosis was established on strong clinical suspicion with presence of grayish black crusting on nasal endoscopy which is confirmed by histopathology examination. Immediate correction of underlying immunocompromised status with debridement with intravenous liposomal amphotericin B was done in all the 26 cases out of which 10 patients were cured. Early detection and aggressive multidisciplinary management is must for the successful treatment of mucormycosis.
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ISSN:2231-3796
0973-7707
DOI:10.1007/s12070-018-1384-6