Swept Source Optical Coherence Tomography Analysis of the Selected Eye’s Anterior Segment Parameters

• Published in: Journal of clinical medicine Vol. 10; no. 5; p. 1094
• Main Authors: Dembski, Michał, Nowińska, Anna, Ulfik-Dembska, Klaudia, Wylęgała, Edward
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 05.03.2021; MDPI
• Subjects: Age groups; Biometrics; Clinical medicine; Cornea; Fourier analysis; Glaucoma; Reproducibility; Software; Tomography; Ultrasonic imaging; Poland; anterior chamber angle; cornea; optical coherence tomography; keratometry
• ISSN: 2077-0383; 2077-0383
• DOI: 10.3390/jcm10051094

Background: The present study determined the mean reference values of the anterior segment parameters of the selected eye using swept source optical coherence tomography (SS-OCT) in healthy Caucasian participants. Methods: A total of 166 volunteers (age 54–79 years), women (n = 92) and men (n = 74), were analyzed. One eye of each subject was randomly selected for anterior segment imaging. The anterior segment of the eye was scanned with CASIA2. The analyzed anterior segment parameters were divided into three groups, namely parameters of the cornea, lens, and angle. Results: The OCT (e.g., Ks, Kf, pKf, pKs, and central corneal thickness) and Fourier parameters of the cornea were significantly different between females and males. The iridocorneal angle was the smallest in the upper quadrant for all distance from the apex of the angle (250, 500, and 750 µm). Conclusions: Therefore, SS-OCT enables the analysis of parameters of the cornea, anterior chamber, lens, and iridocorneal angle, highlighting its clinical utility. Sex-specific differences in the analyzed parameters should be taken into account during the diagnosis of corneal diseases. The configuration of the filtration angle is an important marker during glaucoma diagnosis and drainage implant surgery. Measurements with CASIA 2is characterized by very good repeatability.